Area of research
Genetics · Physiology
Research interest
Research interests include Hemoglobinopathies and Related Disorders, Erythrocyte Function and Pathophysiology, Blood groups and transfusion, and Iron Metabolism and Disorders.
Complement is activated in patients with acute chest syndrome caused by sickle cell disease and represents a therapeutic target
Less-deformable erythrocyte subpopulations biomechanically induce endothelial inflammation in sickle cell disease
Eculizumab for complement mediated thrombotic microangiopathy in sickle cell disease
Microvasculature-on-a-chip for the long-term study of endothelial barrier dysfunction and microvascular obstruction in disease
Clinical Outcomes Associated With Sickle Cell Trait
Contribution of alternative complement pathway to delayed hemolytic transfusion reaction in sickle cell disease
Extracellular fluid tonicity impacts sickle red blood cell deformability and adhesion
Normal saline is associated with increased sickle red cell stiffness and prolonged transit times in a microfluidic model of the capillary system
Losartan therapy decreases albuminuria with stable glomerular filtration and permselectivity in sickle cell anemia
Hydroxyurea effectiveness in children and adolescents with sickle cell anemia: A large retrospective, population‐based cohort
Biochemical surrogate markers of hemolysis do not correlate with directly measured erythrocyte survival in sickle cell anemia
Use of an oral stable isotope label to confirm variation in red blood cell mean age that influences HbA1c interpretation
Erythrocyte NADPH oxidase activity modulated by Rac GTPases, PKC, and plasma cytokines contributes to oxidative stress in sickle cell disease