Area of research
Genetics · Otorhinolaryngology
Research interest
Research interests include Glioma Diagnosis and Treatment, Head and Neck Cancer Studies, Meningioma and schwannoma management, and Lung Cancer Diagnosis and Treatment.
Individualized patient tumor organoids faithfully preserve human brain tumor ecosystems and predict patient response to therapy
Prospective, multicenter validation of a platform for rapid molecular profiling of central nervous system tumors
Spatially resolved transcriptomics and graph-based deep learning improve accuracy of routine CNS tumor diagnostics
Molecularly matched targeted therapies plus radiotherapy in glioblastoma: the phase 1/2a N2M2 umbrella trial
Tumor-associated macrophages in meningiomas: a novel biomarker for poor survival outperforming the benefits of T cells
BRAT1 - a new therapeutic target for glioblastoma
Distinct molecular profile and outcome of oligodendroglioma, <i>IDH</i> -mutant, 1p/19q-codeleted, and <i>TERT</i> p-wildtype: A grade 1 oligodendroglioma of young patients?
P2RY2 is a purinergic immune checkpoint linking extracellular ATP to immune evasion and adaptive resistance to immunotherapy
Delivering precision oncology in metastatic breast cancer: Clinical impact of comprehensive genomic profiling—The <scp>CATCH</scp> experience
Employing nanopore sequencing on FFPE-derived DNA for CNS tumor diagnostics
A framework for using DNA methylation-based modelling for the clinical management of cranial meningioma
Loss of global DNA hypermethylation is prognostic in IDH-mutant and 1p/19q-codeleted oligodendrogliomas
AI-based histopathological classification of central nervous system tumours
Molecular classification to refine surgical and radiotherapeutic decision-making in meningioma
A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
The prognostic impact of <i>CDKN2A/B</i> hemizygous deletions in IDH-mutant glioma
Loss over 5% of chromosome 1p is a clinically relevant and applicable cut-off for increased risk of recurrence in meningioma
The Role of SOX2 and SOX9 in Radioresistance and Tumor Recurrence
Integration of transcriptomics, proteomics and loss-of-function screening reveals WEE1 as a target for combination with dasatinib against proneural glioblastoma
Meningiomas: Sex-specific differences and prognostic implications of a chromosome X loss
Distinct epigenetic and transcriptional profiles of Epstein-Barr virus-positive and negative primary CNS lymphomas
Malformin C preferentially kills glioblastoma stem‐like cells via concerted induction of proteotoxic stress and autophagic flux blockade
Personalized Medicine for Meningiomas: Drug Screening on Tumor Organoids Exposes Therapeutic Vulnerabilities to HDAC1/2i Panobinostat
Prediction of WHO grade and methylation class of aggressive meningiomas: Extraction of diagnostic information from infrared spectroscopic data
Versatile, accessible cross-platform molecular profiling of central nervous system tumors: web-based, prospective multi-center validation
BRAT1 - a new therapeutic target for glioblastoma
Tumor-Associated Macrophages in Meningiomas: An Independent Prognostic Factor for Poor Survival Outperforming the Benefits of T cells
Effective Reprogramming of Patient-Derived M2-Polarized Glioblastoma-Associated Microglia/Macrophages by Treatment with GW2580
Glioneuronal tumor with ATRX alteration, kinase fusion and anaplastic features (GTAKA): a molecularly distinct brain tumor type with recurrent NTRK gene fusions
Tumor heterogeneity and tumor-microglia interactions in primary and recurrent IDH1-mutant gliomas