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Amélie Bonnefond

Inserm · FR
Area of research
Genetics · Surgery
Research interest
Research interests include Pancreatic function and diabetes, Genetic Associations and Epidemiology, Diabetes and associated disorders, and Epigenetics and DNA Methylation.
h-index
61
citations
17,310
works
358
NIH funding
primary concept
Medicine
email

Recent publications

Partitioned polygenic scores show mechanistic heterogeneity in type 2 diabetes and hypertension comorbidity
Nature Communications 2026cited by 0position: middledoi
The Alzheimer’s disease risk gene BIN1 regulates activity-dependent gene expression in human-induced glutamatergic neurons
Molecular Psychiatry 2024cited by 54position: middledoi
Genome-wide meta-analyses of restless legs syndrome yield insights into genetic architecture, disease biology and risk prediction
Nature Genetics 2024cited by 50position: middledoi
Prediction of individual lifetime cardiovascular risk and potential treatment benefit: development and recalibration of the LIFE-CVD2 model to four European risk regions
European Journal of Preventive Cardiology 2024cited by 17position: middledoi
Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits
Nature Communications 2023cited by 50position: middledoi
Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes
Human Molecular Genetics 2022cited by 121position: middledoi
Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study
Cell Reports Medicine 2022cited by 87position: middledoi
Maternal Glycemic Dysregulation During Pregnancy and Neonatal Blood DNA Methylation: Meta-analyses of Epigenome-Wide Association Studies
Diabetes Care 2022cited by 65position: middledoi
The transcription factor E2F1 controls the GLP-1 receptor pathway in pancreatic β cells
Cell Reports 2022cited by 15position: middledoi
Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability
Nature Communications 2021cited by 164position: middledoi
Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability
Nature Communications 2021cited by 7position: middledoi
A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity
Human Molecular Genetics 2019cited by 128position: middledoi
Loss-of-function mutations in ADCY3 cause monogenic severe obesity
Nature Genetics 2018cited by 192position: middledoi
MFN2-associated lipomatosis: Clinical spectrum and impact on adipose tissue
Journal of clinical lipidology 2018cited by 78position: middledoi
Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults
EBioMedicine 2018cited by 33position: middledoi
Meta-Analysis of Maternal Prenatal Smoking GFI1-Locus and Cardio-Metabolic Phenotypes in Adults
SSRN Electronic Journal 2018cited by 0position: middledoi
Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis
PLoS Medicine 2017cited by 439position: middledoi
Genetic evidence of assortative mating in humans
Nature Human Behaviour 2017cited by 367position: middledoi
Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults
PLoS Genetics 2017cited by 339position: middledoi
Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis
The Lancet Neurology 2017cited by 240position: middledoi
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits
Nature Communications 2017cited by 232position: middledoi
Shared genetic predisposition in rheumatoid arthritis-interstitial lung disease and familial pulmonary fibrosis
European Respiratory Journal 2017cited by 230position: middledoi
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
Nature Communications 2016cited by 314position: middledoi
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
PLoS Genetics 2015cited by 688position: middledoi
Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index
Human Molecular Genetics 2015cited by 371position: middledoi
Directional dominance on stature and cognition in diverse human populations
Nature 2015cited by 201position: middledoi
Low copy number of the salivary amylase gene predisposes to obesity
Nature Genetics 2014cited by 263position: middledoi
A nonsense loss-of-function mutation in PCSK1 contributes to dominantly inherited human obesity
International Journal of Obesity 2014cited by 74position: lastdoi
Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits
PLoS Genetics 2013cited by 458position: middledoi
Association between large detectable clonal mosaicism and type 2 diabetes with vascular complications
Nature Genetics 2013cited by 137position: firstdoi

Grants

No grants ingested yet.

Frequent collaborators

Philippe Froguel · Imperial College London8 papers (2012–2022)Michel Marre · Centre National de la Recherche Scientifique5 papers (2012–2013)Olivier Lantieri · BGI Group (China)4 papers (2012–2013) · 4 papers (2012–2013)G. Charpentier · BGI Group (China)4 papers (2012–2013)Loïc Yengo · The University of Queensland3 papers (2012–2013)Julien Philippe · Institut Pasteur3 papers (2012–2014)Aurélie Dechaume · Institut Pasteur3 papers (2012–2013)Martine Vaxillaire · Institut Pasteur2 papers (2012–2012) · 2 papers (2012–2013)Serge Herçberg · Instituto Latinoamericano de Computación2 papers (2012–2013)David Meyre · Hospital for Sick Children2 papers (2012–2014)Stéphane Lobbens · Institut Pasteur2 papers (2012–2013)Olivier Sand · Institut Pasteur2 papers (2012–2014)Oluf Pedersen · European Molecular Biology Laboratory2 papers (2012–2013)Emmanuel Vaillant · Institut Pasteur2 papers (2012–2012)Jérôme Delplanque · Institut Pasteur2 papers (2012–2014)Torben Hansen · Novo Nordisk Foundation2 papers (2012–2013)Franck De Graeve · Institut Pasteur2 papers (2012–2014) · 1 papers (2018–2018)