Area of research
Psychiatry and Mental health · Physiology
Research interest
Research interests include Dementia and Cognitive Impairment Research, Alzheimer's disease research and treatments, Functional Brain Connectivity Studies, and Health, Environment, Cognitive Aging.
Longitudinal analysis of a dominantly inherited Alzheimer disease mutation carrier protected from dementia
Integrative multiomics reveals common endotypes across PSEN1, PSEN2, and APP mutations in familial Alzheimer’s disease
Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer’s disease
Reliability and Validity of Smartphone Cognitive Testing for Frontotemporal Lobar Degeneration
Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer’s disease
Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer’s disease
Amyloid and tau‐PET in early‐onset AD: Baseline data from the Longitudinal Early‐onset Alzheimer's Disease Study (LEADS)
Longitudinal head-to-head comparison of 11C-PiB and 18F-florbetapir PET in a Phase 2/3 clinical trial of anti-amyloid-β monoclonal antibodies in dominantly inherited Alzheimer’s disease
Cerebrospinal fluid biomarkers in the Longitudinal Early‐onset Alzheimer's Disease Study
Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid
Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum
Effect of Race on Prediction of Brain Amyloidosis by Plasma Aβ42/Aβ40, Phosphorylated Tau, and Neurofilament Light
Plasma glial fibrillary acidic protein in autosomal dominant Alzheimer's disease: Associations with Aβ‐PET, neurodegeneration, and cognition
Comprehensive cross-sectional and longitudinal analyses of plasma neurofilament light across FTD spectrum disorders
Autosomal dominant and sporadic late onset Alzheimer's disease share a common<i>in vivo</i>pathophysiology
ASLPrep: a platform for processing of arterial spin labeled MRI and quantification of regional brain perfusion
A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer’s disease
A phase II study repurposing atomoxetine for neuroprotection in mild cognitive impairment
The Longitudinal Early‐onset Alzheimer's Disease Study (LEADS): Framework and methodology
African Americans Have Differences in CSF Soluble TREM2 and Associated Genetic Variants
Resting-State Functional Connectivity Disruption as a Pathological Biomarker in Autosomal Dominant Alzheimer Disease
APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline
A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease
The Alzheimer's Biomarker Consortium‐Down Syndrome: Rationale and methodology
Serum neurofilament light chain levels are associated with white matter integrity in autosomal dominant Alzheimer's disease
Blood–brain barrier breakdown is an early biomarker of human cognitive dysfunction
Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease
An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations
Reactions to Multiple Ascending Doses of the Microtubule Stabilizer TPI-287 in Patients With Alzheimer Disease, Progressive Supranuclear Palsy, and Corticobasal Syndrome
ATN profiles among cognitively normal individuals and longitudinal cognitive outcomes