Andrea Straßer

Label-Free Investigations on the G Protein Dependent Signaling Pathways of Histamine Receptors

Abolishing Dopamine D_2long/D₃ Receptor Affinity of Subtype-Selective Carbamoylguanidine-Type Histamine H₂ Receptor Agonists

Specific Engineered G Protein Coupling to Histamine Receptors Revealed from Cellular Assay Experiments and Accelerated Molecular Dynamics Simulations

Shining light on the histamine H2 receptor: Synthesis of carbamoylguanidine-type agonists as a pharmacological tool to study internalization

Supplementary Materials-Label-free investigations on the G protein dependent signaling pathways of histamine receptors

A Dynamic, Split-Luciferase-Based Mini-G Protein Sensor to Functionally Characterize Ligands at All Four Histamine Receptor Subtypes

A MiniG Protein Recruitment Assay for the Histamine Receptor Family to Functionally Characterize Histamine Receptor Ligands

Structure–Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles

The First Photochromic Affinity Switch for the Human Cannabinoid Receptor 2

Binding Kinetics and Pathways of Ligands to GPCRs

Competitive association binding kinetic assays: a new tool to detect two different binding orientations of a ligand to its target protein under distinct conditions?

Molecular Modelling Approaches for the Analysis of Histamine Receptors and Their Interaction with Ligands

Dibenzo[ b , f ][1,4]oxazepines and dibenzo[ b , e ]oxepines: Influence of the chlorine substitution pattern on the pharmacology at the H 1 R, H 4 R, 5-HT 2A R and other selected GPCRs

Conformational Restriction and Enantioseparation Increase Potency and Selectivity of Cyanoguanidine-Type Histamine H₄Receptor Agonists

Cover Picture: Aminobenzimidazoles and Structural Isomers as Templates for Dual‐Acting Butyrylcholinesterase Inhibitors and <i>h</i>CB₂R Ligands To Combat Neurodegenerative Disorders (ChemMedChem 12/2016)

Aminobenzimidazoles and Structural Isomers as Templates for Dual‐Acting Butyrylcholinesterase Inhibitors and <i>h</i>CB₂R Ligands To Combat Neurodegenerative Disorders

2,4-Diaminopyrimidines as dual ligands at the histamine H1 and H4 receptor—H1/H4-receptor selectivity

Binding pathway of histamine to the hH4R, observed by unconstrained molecular dynamics

Structure-Dependent Deconjugation of Flavonoid Glucuronides by Human β-Glucuronidase – In Vitro and In Silico Analyses

Synthesis, Biological Evaluation, and Computational Studies of Tri- and Tetracyclic Nitrogen-Bridgehead Compounds as Potent Dual-Acting AChE Inhibitors and<i>h</i>H₃Receptor Antagonists

New insights into the cross-linking and degradation mechanism of Diels–Alder hydrogels

Modulation of GPCRs by monovalent cations and anions

Loratadine and Analogues: Discovery and Preliminary Structure–Activity Relationship of Inhibitors of the Amino Acid Transporter B⁰AT2

Sodium binding to hH3R and hH4R — a molecular modeling study

Mathematical analysis of the sodium sensitivity of the human histamine H3 receptor

Pharmacological profile of astemizole-derived compounds at the histamine H1 and H4 receptor—H1/H4 receptor selectivity

Molecular modeling studies give hint for the existence of a symmetric hβ2R-Gαβγ-homodimer

Molecular and cellular analysis of human histamine receptor subtypes

Species-dependent activities of G-protein-coupled receptor ligands: lessons from histamine receptor orthologs

G Protein Coupled Receptors