Area of research
Molecular Biology · Oncology
Research interest
Research interests include DNA Repair Mechanisms, PARP inhibition in cancer therapy, Genomics and Chromatin Dynamics, and CRISPR and Genetic Engineering.
Structural insight into how RAD51 paralog exchange regulates RAD51 filament formation
Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
Tumour-intrinsic PDL1 signals regulate the Chk2 DNA damage response in cancer cells and mediate resistance to Chk1 inhibitors
Regulation of telomere homeostasis and genomic stability in cancer by <i>N</i> <sup>6</sup> -adenosine methylation (m <sup>6</sup> A)
Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer
A Variant of the Breast Cancer Type 2 Susceptibility Protein (BRC) Repeat Is Essential for the RECQL5 Helicase to Interact with RAD51 Recombinase for Genome Stabilization