Area of research
Molecular Biology · Immunology
Research interest
Research interests include Ubiquitin and proteasome pathways, Cell death mechanisms and regulation, interferon and immune responses, and NF-κB Signaling Pathways.
A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death
HSV1 VP1-2 deubiquitinates STING to block type I interferon expression and promote brain infection
Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann–Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn's disease
OTULIN Antagonizes LUBAC Signaling by Specifically Hydrolyzing Met1-Linked Polyubiquitin
X-linked inhibitor of apoptosis (XIAP) deficiency: The spectrum of presenting manifestations beyond hemophagocytic lymphohistiocytosis
The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity