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Alexandra Dürr

Centre National de la Recherche Scientifique · FR
Area of research
Cellular and Molecular Neuroscience · Neurology
Research interest
Research interests include Genetic Neurodegenerative Diseases, Mitochondrial Function and Pathology, Parkinson's Disease Mechanisms and Treatments, and Neurological disorders and treatments.
h-index
120
citations
60,001
works
857
NIH funding
primary concept
email

Recent publications

Predictive models for ataxia progression and conversion in spinocerebellar ataxia type 1 and 3
Brain 2025cited by 2position: middledoi
Copy Number Variation and Haplotype Analysis of <scp>17q21.31</scp> Reveals Increased Risk Associated with Progressive Supranuclear Palsy and Gene Expression Changes in Neuronal Cells
Movement Disorders 2025cited by 1position: middledoi
The Two Faces of Pediatric <scp>SCA2</scp>
European Journal of Neurology 2025cited by 1position: middledoi
Role of the repeat expansion size in predicting age of onset and severity in RFC1 disease
Brain 2024cited by 28position: middledoi
Whole-genome sequencing analysis reveals new susceptibility loci and structural variants associated with progressive supranuclear palsy
Molecular Neurodegeneration 2024cited by 25position: middledoi
SARA captures disparate progression and responsiveness in spinocerebellar ataxias
Journal of Neurology 2024cited by 15position: middledoi
Genotype-specific spinal cord damage in spinocerebellar ataxias: an ENIGMA-Ataxia study
Journal of Neurology Neurosurgery & Psychiatry 2024cited by 14position: middledoi
Somatic instability of the <i>FGF14</i> -SCA27B GAA•TTC repeat reveals a marked expansion bias in the cerebellum
Brain 2024cited by 12position: middledoi
Longitudinal Changes of Clinical, Imaging, and Fluid Biomarkers in Preataxic and Early Ataxic Spinocerebellar Ataxia Type 2 and 7 Carriers
Neurology 2024cited by 11position: lastdoi
Somatic instability of the <i>FGF14</i> -SCA27B GAA•TTC repeat reveals a marked expansion bias in the cerebellum
medRxiv 2024cited by 3position: middledoi
Correction: Whole-genome sequencing analysis reveals new susceptibility loci and structural variants associated with progressive supranuclear palsy
Molecular Neurodegeneration 2024cited by 2position: middledoi
Association of Structural Forms of 17q21.31 with the Risk of Progressive Supranuclear Palsy and <i>MAPT</i> Sub-haplotypes
medRxiv 2024cited by 0position: middledoi
A013 Study of OTX2 transcription factor in Huntington disease
2024cited by 0position: middledoi
Clinical and genetic keys to cerebellar ataxia due to FGF14 GAA expansions
EBioMedicine 2023cited by 54position: lastdoi
Extreme phenotypic heterogeneity in non-expansion spinocerebellar ataxias
The American Journal of Human Genetics 2023cited by 31position: lastdoi
Fast and reliable detection of repeat expansions in spinocerebellar ataxia using exomes
Journal of Medical Genetics 2023cited by 20position: lastdoi
Consensus Recommendations for Clinical Outcome Assessments and Registry Development in Ataxias: Ataxia Global Initiative (AGI) Working Group Expert Guidance
The Cerebellum 2023cited by 20position: middledoi
Whole-Genome Sequencing Analysis Reveals New Susceptibility Loci and Structural Variants Associated with Progressive Supranuclear Palsy
medRxiv 2023cited by 8position: middledoi
Paving the Way Toward Meaningful Trials in Ataxias: An Ataxia Global Initiative Perspective
Movement Disorders 2022cited by 44position: middledoi
De Novo and Dominantly Inherited <scp><i>SPTAN1</i></scp> Mutations Cause Spastic Paraplegia and Cerebellar Ataxia
Movement Disorders 2022cited by 25position: middledoi
Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology
Nature Genetics 2022cited by 4position: middledoi
Sensory and corticospinal signs before ataxia onset in SCA1 and SCA3: the READISCA study
HAL (Le Centre pour la Communication Scientifique Directe) 2022cited by 0position: middle
Temporal Dynamics of the Scale for the Assessment and Rating of Ataxia in Spinocerebellar Ataxias.
DZNE Pub 2022cited by 0position: middle
Clinical and genetic spectra of 1550 index patients with hereditary spastic paraplegia
Brain 2021cited by 68position: middledoi
Plasma neurofilament light chain predicts cerebellar atrophy and clinical progression in spinocerebellar ataxia
Neurobiology of Disease 2021cited by 67position: lastdoi
Biallelic loss-of-function variations in PRDX3 cause cerebellar ataxia
Brain 2021cited by 33position: middledoi
Questioning the causality of HTT CAG-repeat expansions in FTD/ALS
Neuron 2021cited by 11position: lastdoi
Serum NfL in spinocerebellar ataxia type 1 is increased already at the preataxic stage, correlating with proximity to clinical onset
medRxiv 2021cited by 1position: middledoi
Machine learning spots the time to treat Huntington disease
Research Square 2021cited by 0position: lastdoi
Clinical, neuropathological, and genetic characterization of STUB1 variants in cerebellar ataxias: a frequent cause of predominant cognitive impairment
Genetics in Medicine 2020cited by 49position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Sarah J. Tabrizi · Huntington's Disease Association18 papers (2012–2021)Blair R. Leavitt · University of British Columbia Hospital12 papers (2012–2019)Raymund A.C. Roos · UK Dementia Research Institute12 papers (2012–2019)Rachael I. Scahill · Huntington's Disease Association11 papers (2012–2021)Alexis Brice · Methodist Dallas Medical Center10 papers (2012–2024)Chris Frost · London School of Hygiene & Tropical Medicine10 papers (2012–2017)G. Bernhard Landwehrmeyer · University of Iowa8 papers (2012–2019)Giovanni Stévanin · Centre Hospitalier Universitaire de Bordeaux8 papers (2013–2021)Douglas R. Langbehn · London School of Hygiene & Tropical Medicine8 papers (2012–2019)Gail Owen · University of Leicester7 papers (2013–2019)Lüdger Schöls · German Center for Neurodegenerative Diseases6 papers (2012–2021)Ralf Reilmann · University of Rochester Medical Center5 papers (2013–2019)Matthis Synofzik · University of Antwerp5 papers (2013–2022)Beth Borowsky · UK Dementia Research Institute5 papers (2013–2019) · 5 papers (2012–2016)David Craufurd · University of Iowa5 papers (2013–2019)Nicola Z. Hobbs · London School of Hygiene & Tropical Medicine5 papers (2012–2015)Giulia Coarelli · Università Cattolica del Sacro Cuore5 papers (2021–2024)Emilien Petit · Centre National de la Recherche Scientifique4 papers (2021–2024)Tetsuo Ashizawa · Cornell University4 papers (2022–2024)