Area of research
Epidemiology · Hepatology
Research interest
Research interests include Hepatitis B Virus Studies, Hepatitis C virus research, Liver Disease Diagnosis and Treatment, and Liver Disease and Transplantation.
Role of malate dehydrogenase 1 and isocitrate dehydrogenase 1 and their posttranslational modifications in diseases.
The Role of Extracellular Histones in Disease Progression: A Potential Therapeutic Target for Disease Modulation.
Pyruvate Kinase M2 Links Metabolism and Epigenetics: A New Target for Liver Disease Treatment.
IDH1/MDH1 deacetylation promotes acute liver failure by regulating NETosis.
Deacetylated MDH1 and IDH1 aggravates PANoptosis in acute liver failure through endoplasmic reticulum stress signaling.
Vacancy-rich Fe-Ce mixed oxides as nanoenzymes for efficient antioxidant activity in vitro
MPO-DNA Complexes and cf-DNA in Patients with Sepsis and Their Clinical Value.
IDH1/MDH1 deacetylation promotes NETosis by regulating OPA1 and autophagy.
Metabolic Dysregulation and Metabolite Imbalances in Acute-on-chronic Liver Failure: Impact on Immune Status.
PANoptosis: A Cell Death Characterized by Pyroptosis, Apoptosis, and Necroptosis.
Distinct Types of Cell Death and Implications in Liver Diseases: An Overview of Mechanisms and Application.
NOD2-mediated HDAC6/NF-κb signalling pathway regulates ferroptosis induced by extracellular histone H3 in acute liver failure.
Interventions for non-alcoholic liver disease: a gut microbial metabolites perspective.
Histone deacetylase 2 regulates ULK1 mediated pyroptosis during acute liver failure by the K68 acetylation site.
Efficacy and safety of a nanoparticle therapeutic vaccine in patients with chronic hepatitis B: A randomized clinical trial
HDAC6 inhibitor ACY1215 inhibits the activation of NLRP3 inflammasome in acute liver failure by regulating the ATM/F-actin signalling pathway.
Histone Deacetylase 6 Regulates the Activation of M1 Macrophages by the Glycolytic Pathway During Acute Liver Failure.
Role of SIRT1 in Hepatic Encephalopathy: In Vivo and In Vitro Studies Focusing on the NLRP3 Inflammasome.
The relationship between liver pathological inflammation degree and pyroptosis in chronic hepatitis B patients.
Clinical characteristics of 25 death cases with COVID-19: A retrospective review of medical records in a single medical center, Wuhan, China.
The Beneficial Roles of SIRT1 in Neuroinflammation-Related Diseases.
TNF-α/HMGB1 inflammation signalling pathway regulates pyroptosis during liver failure and acute kidney injury.
Artificial neural network-based models used for predicting 28- and 90-day mortality of patients with hepatitis B-associated acute-on-chronic liver failure
AGK2 Alleviates Lipopolysaccharide Induced Neuroinflammation through Regulation of Mitogen-Activated Protein Kinase Phosphatase-1.
SENP7 knockdown inhibited pyroptosis and NF-κB/NLRP3 inflammasome pathway activation in Raw 264.7 cells.
Efficacy of a Chinese herbal formula on hepatitis B e antigen-positive chronic hepatitis B patients
Efficacy and Safety of All-oral Emitasvir and Sofosbuvir in Patients with Genotype 1b HCV Infections without Cirrhosis
Clinical characteristics of 25 death cases with COVID-19: a retrospective review of medical records in a single medical center, Wuhan, China
Clinical Challenges in an Outbreak of COVID-19 in Wuhan, China: Concerns from Frontiers.
Betaine Inhibits Toll-like Receptor 4 Responses and Restores Intestinal Microbiota in Acute Liver Failure Mice