Area of research
Cellular and Molecular Neuroscience · Molecular Biology
Research interest
Research interests include Nuclear Receptors and Signaling, Retinoids in leukemia and cellular processes, Pluripotent Stem Cells Research, and Estrogen and related hormone effects.
Transcriptomic atlas of midbrain dopamine neurons uncovers differential vulnerability in a Parkinsonism lesion model
Schwann cell precursors represent a neural crest‐like state with biased multipotency
Disease Duration Influences Gene Expression in Neuromelanin-Positive Cells From Parkinson’s Disease Patients
Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease
CYCLIN-B1/2 and -D1 act in opposition to coordinate cortical progenitor self-renewal and lineage commitment
Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development
A comprehensive map coupling histone modifications with gene regulation in adult dopaminergic and serotonergic neurons
Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson’s Disease
Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages
Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons
Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease
Nurr1 and Retinoid X Receptor Ligands Stimulate Ret Signaling in Dopamine Neurons and Can Alleviate α-Synuclein Disrupted Gene Expression
Modulation by Trace Amine-Associated Receptor 1 of Experimental Parkinsonism, l-DOPA Responsivity, and Glutamatergic Neurotransmission
Sox6 and Otx2 Control the Specification of Substantia Nigra and Ventral Tegmental Area Dopamine Neurons
NURR1 in Parkinson disease—from pathogenesis to therapeutic potential
Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons
Detailed Expression Analysis of Regulatory Genes in the Early Developing Human Neural Tube
α-Synuclein–Induced Down-Regulation of Nurr1 Disrupts GDNF Signaling in Nigral Dopamine Neurons
Maintaining differentiated cellular identity