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Changlin Yang

BGI Group (China) · CN
Area of research
Oncology · Genetics
Research interest
Research interests include Glioma Diagnosis and Treatment, Immunotherapy and Immune Responses, CAR-T cell therapy research, and Cancer Immunotherapy and Biomarkers.
h-index
17
citations
1,441
works
119
NIH funding
primary concept
email

Recent publications

IMMU-79. An Updated Analysis of PD1 and Immune Pathway Activity in Malignant Pediatric Central Nervous System (CNS) Tumors: A Pediatric Brain Tumor Consortium (PBTC) Study, PBTC-N13
Neuro-Oncology 2025cited by 0position: middledoi
Adeno-associated virus delivered CXCL9 sensitizes glioblastoma to anti-PD-1 immune checkpoint blockade
Nature Communications 2024cited by 19position: middledoi
KR158 spheres harboring slow-cycling cells recapitulate GBM features in an immunocompetent system
bioRxiv (Cold Spring Harbor Laboratory) 2024cited by 2position: middledoi
Effects of immune checkpoint blockade on antigen‐specific CD8<sup>+</sup> T cells for use in adoptive cellular therapy
Microbiology and Immunology 2022cited by 10position: middledoi
Immune Escape After Adoptive T-cell Therapy for Malignant Gliomas
Clinical Cancer Research 2020cited by 46position: middledoi
Dendritic Cell-Activating Magnetic Nanoparticles Enable Early Prediction of Antitumor Response with Magnetic Resonance Imaging
ACS Nano 2019cited by 91position: middledoi
Massive clonal expansion of medulloblastoma-specific T cells during adoptive cellular therapy
Science Advances 2019cited by 28position: middledoi
ATIM-15. SUSTAINED COMPLETE RADIOGRAPHIC RESPONSE AND PROLONGED SYSTEMIC IMMUNE ACTIVATION IN A PATIENT WITH MGMT UNMETHYLATED MIDLINE GLIOBLASTOMA RECEIVING CMV pp65-LAMP RNA-PULSED DENDRITIC CELL VACCINES
Neuro-Oncology 2019cited by 3position: middledoi
ATIM-34. SINGLE-CELL RNA SEQUENCING REVEALS DYNAMIC IMMUNE RESPONSE CHANGES IN GLIOBLASTOMA PATIENT WITH DURABLE COMPLETE RESPONSE TO CMV PP65-LAMP RNA-PULSED DENDRITIC VACCINES
Neuro-Oncology 2019cited by 1position: middledoi
TMIC-29. METABOLIC INTERACTIONS BETWEEN TREATMENT-RESISTANT SLOW-CYCLING CELLS AND THE IMMUNE SYSTEM IN HIGH-GRADE GLIOMA
Neuro-Oncology 2019cited by 0position: middledoi
IMMU-13. MECHANISMS OF IMMUNOLOGICAL ESCAPE DURING ADOPTIVE CELLULAR THERAPY IN HIGH GRADE GLIOMA
Neuro-Oncology 2019cited by 0position: middledoi
IMMU-24. A COMPREHENSIVE IN SILICO APPROACH TO DISCOVERING TUMOR REJECTION ANTIGENS IN MALIGNANT BRAIN TUMORS
Neuro-Oncology 2019cited by 0position: firstdoi
IMMU-27. IMMUNE CHECKPOINT BLOCKADE OF EX VIVO EXPANDED T CELLS FOR USE IN ADOPTIVE CELLULAR THERAPY (ACT) FOR GLIOBLASTOMA
Neuro-Oncology 2019cited by 0position: middledoi
EXTH-15. INCREASING THE TRAFFICKING OF DENDRITIC CELLS VIA CXC CHEMOKINE SIGNALING PATHWAY LEADS TO IMPROVED ANTI-TUMOR EFFICACY OF DENDRITIC CELL VACCINES
Neuro-Oncology 2019cited by 0position: middledoi
The IDH1 Mutation-Induced Oncometabolite, 2-Hydroxyglutarate, May Affect DNA Methylation and Expression of PD-L1 in Gliomas
Frontiers in Molecular Neuroscience 2018cited by 86position: middledoi
IMMU-45. DOSE MODULATION OF TEMOZOLOMIDE HAVE DISTINCT EFFECTS ON HOST RESPONSE TO PD-1 BLOCKADE
Neuro-Oncology 2018cited by 1position: middledoi
IMMU-56. CXCR1/2 MODIFIED CARs CO-OPT RADIATION-INDUCED IL-8 FOR ENHANCED CHEMOTAXIS OF THE CAR T CELLS AND MAXIMAL ANTI-TUMOR EFFICACY
Neuro-Oncology 2018cited by 0position: middledoi
IMMU-43. RNA-MODIFIED T CELLS AS A NON-INVASIVE AND EFFICACIOUS STRATEGY TO DELIVER THERAPEUTIC MACROMOLECULES LOCALLY TO INTRACRANIAL TUMORS
Neuro-Oncology 2018cited by 0position: middledoi
STEM-09. CANCER STEM CELL IMMUNOEDITING
Neuro-Oncology 2018cited by 0position: middledoi
CD70, a novel target of CAR T-cell therapy for gliomas
Neuro-Oncology 2017cited by 223position: middledoi
Tumor associated CD70 expression is involved in promoting tumor migration and macrophage infiltration in GBM
International Journal of Cancer 2017cited by 116position: middledoi
CD4+ and Perivascular Foxp3+ T Cells in Glioma Correlate with Angiogenesis and Tumor Progression
Frontiers in Immunology 2017cited by 54position: middledoi
CD70 as a novel target of CAR-T-cell therapy for gliomas.
Journal of Clinical Oncology 2017cited by 4position: middledoi
CD70 as a critical mediator of tumor progression and immunosuppression in gliomas.
Journal of Clinical Oncology 2017cited by 2position: firstdoi
TMIC-26. IMMUNOMODULATION WITH TEMOZOLOMIDE TO IMPROVE EFFICACY OF IMMUNE CHECKPOINT INHIBITION FOR THE TREATMENT OF GLIOBLASTOMA
Neuro-Oncology 2017cited by 1position: middledoi
STEM-09. TREATMENT-RESISTANT SLOW-CYCLING CELLS SUPPORT METABOLIC HETEROGENEITY AND ADAPTABILITY IN GLIOBLASTOMA
Neuro-Oncology 2017cited by 0position: middledoi
IMMU-25. ENHANCED T CELLS TUMOR RECOGNITION USING DENDRITIC CELLS PULSED WITH CHIMERIC RNAs ENCODING FULL-LENGTH LAMP-1 FUSION CONSTRUCTS
Neuro-Oncology 2017cited by 0position: firstdoi
TMIC-12. TMZ RESULTS IN PRIMING OF HOST IMMUNITY AND CHANGES IN GBM TUMOR PDL-1 EXPRESSION IN A DOSE DEPENDENT FASHION THAT CAN BE LEVERAGED FOR COMBINATION WITH IMMUNE CHECKPOINT BLOCKADE
Neuro-Oncology 2016cited by 1position: middledoi
IMST-33. ENHANCED T CELL ACTIVATION USING DENDRITIC CELLS PULSED WITH CHIMERIC RNAs ENCODING FULL-LENGTH LAMP-1 FUSION CONSTRUCTS
Neuro-Oncology 2016cited by 1position: firstdoi
IMST-24. COMBINATION OF VEGF-A AND PD-1 BLOCKADE MAY ENHANCE ANTITUMOR EFFICACY IN GBM
Neuro-Oncology 2016cited by 0position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Duane A. Mitchell · Allen Institute for Brain Science34 papers (2015–2025)Jianping Huang · Fujian Normal University22 papers (2015–2024)Elias Sayour · Allen Institute for Brain Science15 papers (2015–2019)Paul Kubilis · University of Florida10 papers (2016–2018)Linchun Jin · University of Florida10 papers (2015–2018)Jeffrey Drake · The University of Texas MD Anderson Cancer Center9 papers (2015–2022)Haitao Ge · The First Affiliated Hospital, Sun Yat-sen University9 papers (2015–2018)Catherine Flores · Allen Institute for Brain Science8 papers (2015–2020)Maryam Rahman · University of Florida Health8 papers (2016–2019)Luyan Mu · Harbin Medical University8 papers (2015–2018)Aida Karachi · Allen Institute for Brain Science8 papers (2016–2019)Yifan Chang · University of Florida8 papers (2015–2018)Loic P. Deleyrolle · Jacksonville College7 papers (2016–2024)Oleg Yegorov · University of Florida7 papers (2019–2024)Anjelika Dechkovskaia · University of Florida7 papers (2016–2022)Zhiguo Lin · Harbin Medical University7 papers (2015–2018)Jesse Kresak · University of Florida6 papers (2017–2024)Adam Grippin · The University of Texas MD Anderson Cancer Center6 papers (2018–2024)Jiping Qi · Harbin Medical University6 papers (2015–2018)Kyle Dyson · Stanford University6 papers (2018–2020)