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Chenghua Gu

Howard Hughes Medical Institute · US
Area of research
Cellular and Molecular Neuroscience · Neurology
Research interest
Research interests include Barrier Structure and Function Studies, Axon Guidance and Neuronal Signaling, Angiogenesis and VEGF in Cancer, and Neuroscience and Neuropharmacology Research.
h-index
46
citations
10,286
works
76
NIH funding
primary concept
email

Recent publications

Brain endothelial gap junction coupling enables rapid vasodilation propagation during neurovascular coupling
Cell 2025cited by 19position: lastdoi
Cerebral blood flow and energy demand: imaging insights into neurovascular function
Neurophotonics 2025cited by 1position: lastdoi
Characteristics of blood–brain barrier heterogeneity between brain regions revealed by profiling vascular and perivascular cells
Nature Neuroscience 2024cited by 73position: lastdoi
The secreted neuronal signal Spock1 promotes blood-brain barrier development
Developmental Cell 2023cited by 31position: middledoi
Endothelial-endothelial signaling as a mechanism for neurovascular coupling
Physiology 2023cited by 1position: lastdoi
Pericyte-to-endothelial cell signaling via vitronectin-integrin regulates blood-CNS barrier
Neuron 2022cited by 160position: lastdoi
A high-efficiency AAV for endothelial cell transduction throughout the central nervous system
Nature Cardiovascular Research 2022cited by 105position: middledoi
Neuronal regulation of the blood–brain barrier and neurovascular coupling
Nature reviews. Neuroscience 2020cited by 421position: lastdoi
Caveolae in CNS arterioles mediate neurovascular coupling
Nature 2020cited by 235position: lastdoi
Cortical ChAT+ neurons co-transmit acetylcholine and GABA in a target- and brain-region-specific manner
eLife 2020cited by 168position: middledoi
Development and Cell Biology of the Blood-Brain Barrier
Annual Review of Cell and Developmental Biology 2019cited by 501position: lastdoi
Transcytosis at the blood–brain barrier
Current Opinion in Neurobiology 2019cited by 289position: lastdoi
Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis
Neuron 2017cited by 616position: lastdoi
“Small Blood Vessels: Big Health Problems?”: Scientific Recommendations of the National Institutes of Health Workshop
Journal of the American Heart Association 2016cited by 84position: middledoi
Temporal modulation of collective cell behavior controls vascular network topology
eLife 2016cited by 31position: lastdoi
Joint volumetric extraction and enhancement of vasculature from low-SNR 3-D fluorescence microscopy images
Pattern Recognition 2016cited by 6position: middledoi
The Molecular Constituents of the Blood–Brain Barrier
Trends in Neurosciences 2015cited by 383position: lastdoi
Neuronal and Vascular Interactions
Annual Review of Neuroscience 2015cited by 257position: lastdoi
Mfsd2a is critical for the formation and function of the blood–brain barrier
Nature 2014cited by 1,018position: lastdoi
Midbrain dopamine neurons sustain inhibitory transmission using plasma membrane uptake of GABA, not synthesis
eLife 2014cited by 200position: middledoi
Neuropilin-1 functions as a VEGFR2 co-receptor to guide developmental angiogenesis independent of ligand binding
eLife 2014cited by 143position: lastdoi
Multiphasic Modulation of Cholinergic Interneurons by Nigrostriatal Afferents
Journal of Neuroscience 2014cited by 136position: middledoi
Neuroligin-1–dependent competition regulates cortical synaptogenesis and synapse number
Nature Neuroscience 2012cited by 187position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Luke Kaplan · Harvard University Press5 papers (2020–2025)Bernardo L. Sabatini · Harvard University5 papers (2012–2020)Baptiste Lacoste · McGill University Health Centre5 papers (2014–2017) · 5 papers (2015–2020)Won‐Jong Oh · Korea Brain Research Institute3 papers (2012–2014)Swathi Ayloo · AVEO Oncology (United States)3 papers (2019–2022)Daniel Ryvkin · Howard Hughes Medical Institute3 papers (2022–2025)Trevor Krolak · Howard Hughes Medical Institute3 papers (2022–2025)Aleksandra Tata · Duke Medical Center3 papers (2014–2017)Benjamin J. Andreone · University of Massachusetts Boston3 papers (2014–2017)Ayal Ben Zvi · Hebrew University of Jerusalem3 papers (2014–2017)Zhuhao Wu · Cornell University2 papers (2024–2025)Karina Bistrong · Neurosciences Institute2 papers (2020–2020)Nicolas X. Tritsch · Douglas Mental Health University Institute2 papers (2014–2014)Urs H. Langen · Roche (Switzerland)2 papers (2019–2024)Adam Granger · Broad Institute2 papers (2020–2020)Nellwyn Hagan · Brown University2 papers (2014–2014)Lujing Chen · Dongguan People’s Hospital2 papers (2023–2025)Victoria Izsa · Howard Hughes Medical Institute2 papers (2023–2025)Vicente Nuñez · University of California System2 papers (2020–2020)