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H. Isaac Chen

Guangxi Medical University · CN
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Area of research
Cognitive Neuroscience · Oncology
Research interest
Research interests include Functional Brain Connectivity Studies, Cancer Cells and Metastasis, Neural dynamics and brain function, and Spinal Fractures and Fixation Techniques.
h-index
11
citations
2,436
works
16
NIH funding
primary concept
email

Recent publications

Brain-wide neuronal circuit connectome of human glioblastoma
Nature 2025cited by 57position: middledoi
Single-cell multi-cohort dissection of the schizophrenia transcriptome
Science 2024cited by 125position: middledoi
Massively parallel characterization of regulatory elements in the developing human cortex
Science 2024cited by 61position: middledoi
Molecular landscapes of human hippocampal immature neurons across lifespan
Nature 2022cited by 304position: middledoi
Sliced Human Cortical Organoids for Modeling Distinct Cortical Layer Formation
Cell stem cell 2020cited by 481position: middledoi
A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity
Cell 2019cited by 1,094position: middledoi

Grants

SBIR Phase II: Scalable Manufacturing of Supramolecular Polymers for Regenerative Medicine
NSF2422766$1,000,0002024–2026PIRePORTER
SBIR Phase I: Efficient Arithmetic on Quasi-Compressed Data for Performance Improvement
NSF2111696$256,0002022–2023PIRePORTER
SBIR Phase I: Scalable Manufacturing of Supramolecular Polymers for Regenerative Medicine
NSF2151711$252,9062022–2023PIRePORTER
CAREER:Real-Time Nonparametric Machine Learning for Healthcare with Guarantees
NSF2047981$583,9102021–2026PIRePORTER
EAPSI: Understanding Alzheimer's Disease through Modifying the Electrical Stability between Two Key Amino Acids of an Important Protein
NSF1515384$5,0702015–2016PIRePORTER
MRI: Acquisition of an LC/MS/MS System for Multidisciplinary Research and Educational Projects
NSF1338088$456,5492013–2018PIRePORTER
Workshop: Fundamental Research Needs in Photonic Materials Synthesis and Processing at the Interface; Rochester, NY; April 28-30, 2003
NSF0321839$51,8282003–2004PIRePORTER
Glassy Liquid Crystals for Reflective Coloration and Optical Storage
NSF0204827$339,0212002–2005PIRePORTER
Vitrified Liquid Crystalline Films: Material Synthesis and Optical Properties
NSF9818234$285,1561999–2002PIRePORTER
Engineering Research Equipment: Luminescence Spectrometer for Polarized Light Emission from Liquid Crystalline Glassy Films
NSF9811172$29,3801998–1999PIRePORTER
Novel Molar Design Concept for Low Molar Mass Glass-Forming Liquid Crystals
NSF9500737$170,0021996–1998PIRePORTER
ENGINEERING RESEARCH EQUIPMENT: Differential Scanning Calorimeter for Liquid Crystal Research
NSF9411604$22,6451994–1996PIRePORTER
Software Engineering Lab with Integrated Software Tools
NSF9250222$64,0001992–1995PIRePORTER
Numerical Techniques of Dynamic Delamination Buckling and Growth in Laminated Structures
NSF9003883$29,8961990–1991PIRePORTER
Expedited Award: Thermotropic Behavior and Novel Applications for Polymer Liquid Crystals
NSF8714924$30,0001987–1989PIRePORTER
Engineering Research Equipment Grant: Binary Tracer Diffusion in Near-Critical and Supercritical Dense Gases
NSF8618176$20,0001987–1988PIRePORTER
A Program of Neutrino Physics Experiments at LAMPF
NSF8501559$1,436,7841985–1988PIRePORTER
Structure and Dynamics of DNA by Electric Dichroism
NSF8506811$102,0001985–1989PIRePORTER
Research Equipment: Diffusion of Aromatic Hydrocarbons in Dense Fluids up to the Supercritical Region
NSF8500974$26,8771985–1987PIRePORTER
Acquisition of a Data Analysis Facility for a Program of Neutrino Physics Experiments
NSF8319297$120,0001984–1985PIRePORTER
Research Initiation: Temperature and Concentration Studies Of Binary Diffusion in Liquids: Equipment Supplement
NSF8305649$53,0001983–1985PIRePORTER
Neutrino Physics Experiments at the Los Alamos Meson PhysicsFacility
NSF8205709$1,254,7871982–1985PIRePORTER
Basic Mechanism to Achieve Clean Combustion of Oil Shale in Fluidized Beds
NSF8113362$29,3591981–1982PIRePORTER
Mathematical and Physical Modelling of the Electroslag Remelting Process
NSF7819699$202,3821979–1981PIRePORTER
Neutrino Electron Elastic Scattering at Los Alamos Meson Physics Facility
NSF7523206$1,919,1491977–1983PIRePORTER

Frequent collaborators

Guo‐li Ming · University of Pennsylvania3 papers (2019–2022)Hongjun Song · Neurosciences Institute3 papers (2019–2022)Fadi Jacob · Emory University3 papers (2019–2022)Yijing Su · Guangxi University2 papers (2020–2022)Xuyu Qian · Boston Children's Hospital2 papers (2019–2020)Hao Wu · Boston Children's Hospital2 papers (2020–2022)Xiaosong Gu · Nanjing University of Chinese Medicine2 papers (2020–2022)Shiying Li · Nantong University2 papers (2020–2022)Phuong Nguyen · Broad Institute2 papers (2019–2020)Ryan Salinas · University of Pennsylvania2 papers (2019–2022)Timothy Lucas · University of Pennsylvania2 papers (2019–2022) · 1 papers (2020–2020)Zev A. Binder · Champions Oncology (United States)1 papers (2019–2019)Ahmet Höke · Johns Hopkins University1 papers (2020–2020)Christopher D. Adam · California University of Pennsylvania1 papers (2020–2020)Sarshan R. Pather · Johns Hopkins Medicine1 papers (2020–2020)Zhexing Wen · Emory University1 papers (2020–2020)Daniel R. Weinberger · Johns Hopkins University1 papers (2022–2022)Steven Brem · Translational Therapeutics (United States)1 papers (2019–2019)Allison Bond · University of California System1 papers (2022–2022)
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