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Francisco Bezanilla

Valparaiso University · US
Area of research
Cellular and Molecular Neuroscience · Molecular Biology
Research interest
Research interests include Ion channel regulation and function, Neuroscience and Neural Engineering, Cardiac electrophysiology and arrhythmias, and Photoreceptor and optogenetics research.
h-index
81
citations
24,015
works
421
NIH funding
primary concept
email

Recent publications

A mechanistic reinterpretation of fast inactivation in voltage-gated Na+ channels
Nature Communications 2023cited by 45position: lastdoi
Noncanonical electromechanical coupling paths in cardiac hERG potassium channel
Nature Communications 2023cited by 42position: middledoi
Optocapacitance: physical basis and its application
Biophysical Reviews 2022cited by 28position: lastdoi
Molecular basis for functional connectivity between the voltage sensor and the selectivity filter gate in Shaker K+ channels
eLife 2021cited by 27position: lastdoi
Remote nongenetic optical modulation of neuronal activity using fuzzy graphene
Proceedings of the National Academy of Sciences 2020cited by 83position: middledoi
Loss-of-function BK channel mutation causes impaired mitochondria and progressive cerebellar ataxia
Proceedings of the National Academy of Sciences 2020cited by 80position: middledoi
Transient Electrical Currents Mediated by the Na+/K+-ATPase: A Tour from Basic Biophysics to Human Diseases
Biophysical Journal 2020cited by 22position: middledoi
An atlas of nano-enabled neural interfaces
Nature Nanotechnology 2019cited by 178position: middledoi
Nongenetic optical neuromodulation with silicon-based materials
Nature Protocols 2019cited by 85position: middledoi
Noncanonical mechanism of voltage sensor coupling to pore revealed by tandem dimers of Shaker
Nature Communications 2019cited by 39position: lastdoi
Photoelectrochemical modulation of neuronal activity with free-standing coaxial silicon nanowires
Nature Nanotechnology 2018cited by 236position: middledoi
Gating currents
The Journal of General Physiology 2018cited by 98position: firstdoi
Development of a PET radioligand for potassium channels to image CNS demyelination
Scientific Reports 2018cited by 59position: middledoi
Cholesterol Functionalization of Gold Nanoparticles Enhances Photoactivation of Neural Activity
ACS Chemical Neuroscience 2018cited by 38position: middledoi
Determination of the Stoichiometry between α- and γ1 Subunits of the BK Channel Using LRET
Biophysical Journal 2018cited by 18position: middledoi
Optocapacitive Generation of Action Potentials by Microsecond Laser Pulses of Nanojoule Energy
Biophysical Journal 2017cited by 89position: lastdoi
Roadmap on semiconductor–cell biointerfaces
Physical Biology 2017cited by 56position: middledoi
Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET
Proceedings of the National Academy of Sciences 2017cited by 37position: middledoi
Heterogeneous silicon mesostructures for lipid-supported bioelectric interfaces
Nature Materials 2016cited by 166position: middledoi
A Novel Voltage Sensor in the Orthosteric Binding Site of the M2 Muscarinic Receptor
Biophysical Journal 2016cited by 49position: middledoi
Elucidation of the Covalent and Tertiary Structures of Biologically Active Ts3 Toxin
Angewandte Chemie International Edition 2016cited by 19position: middledoi
Photosensitivity of Neurons Enabled by Cell-Targeted Gold Nanoparticles
Neuron 2015cited by 361position: lastdoi
Resting state of the human proton channel dimer in a lipid bilayer
Proceedings of the National Academy of Sciences 2015cited by 83position: middledoi
Mechanism of potassium ion uptake by the Na+/K+-ATPase
Nature Communications 2015cited by 79position: middledoi
Kv3.1 uses a timely resurgent K+ current to secure action potential repolarization
Nature Communications 2015cited by 72position: lastdoi
Single-molecule fluorimetry and gating currents inspire an improved optical voltage indicator
eLife 2015cited by 32position: lastdoi
Functional Site-Directed Fluorometry
Advances in experimental medicine and biology 2015cited by 30position: lastdoi
Moving gating charges through the gating pore in a Kv channel voltage sensor
Proceedings of the National Academy of Sciences 2014cited by 79position: lastdoi
Real-Time Imaging of Electrical Signals with an Infrared FDA-Approved Dye
Biophysical Journal 2014cited by 66position: lastdoi
A repulsion mechanism explains magnesium permeation and selectivity in CorA
Proceedings of the National Academy of Sciences 2014cited by 39position: middledoi

Grants

Properties of the Sodium and Potassium Channels from Squid Optic Nerve Incorporated into Lipid Bilayers
NSF8610434$20,0001987–1990PIRePORTER
Voltage Dependence of the Sodium-Calcium Exchange in Squid Axon
NSF8312953$27,9031984–1986PIRePORTER

Frequent collaborators

João L. Carvalho-de-Souza · Midwestern University11 papers (2015–2021)Jérôme J. Lacroix · National Agency for New Technologies, Energy and Sustainable Economic Development9 papers (2012–2018)Michael F. Priest · Northwestern University6 papers (2013–2016)Tomoya Kubota · Osaka Gakuin University6 papers (2013–2020)Bozhi Tian · University of Chicago5 papers (2016–2019)Carlos A. Villalba‐Galea · University of the Pacific5 papers (2012–2013)Bobo Dang · Westlake University5 papers (2013–2017)Stephen B. H. Kent · University of Illinois Chicago5 papers (2013–2017)Ramón Latorre · University of Vermont4 papers (2015–2020)Jeremy S. Treger · University of Chicago4 papers (2014–2015)Carlos A Z Bassetto · University of Chicago4 papers (2021–2023)Yuanwen Jiang · Nanjing Institute of Technology4 papers (2016–2019)Ana M. Correa · Universidade Federal de Minas Gerais4 papers (2014–2017)Bernardo I. Pinto · University of Chicago4 papers (2017–2023)Benoît Roux · University of Chicago3 papers (2012–2015)Ludivine Frezza · University of Chicago3 papers (2013–2014)David R. Pepperberg · University of Illinois Chicago3 papers (2015–2018)Eduardo Perozo · Neurosciences Institute3 papers (2012–2015)Miguel Holmgren · National Human Genome Research Institute3 papers (2012–2020)Fabiana V. Campos · Universidade Federal de Ouro Preto3 papers (2012–2014)