Area of research
Genetics · Immunology
Research interest
Research interests include Inflammatory Bowel Disease, Microscopic Colitis, Ion Channels and Receptors, and Immune Cell Function and Interaction.
The IL-22–oncostatin M axis promotes intestinal inflammation and tumorigenesis
Epithelial OPA1 links mitochondrial fusion to inflammatory bowel disease
A transcriptional atlas of gut-innervating neurons reveals activation of interferon signaling and ferroptosis during intestinal inflammation
Enteric nervous system-derived VIP restrains differentiation of LGR5+ stem cells toward the secretory lineage impeding type 2 immune programs
Single-cell microbiota phenotyping reveals distinct disease and therapy-associated signatures in Crohn’s disease
Pharmacological inhibitors of the gamma-secretase enzyme complex disrupt epithelial cell function triggering colitis in mice
IL-36 signaling as a drug target in Crohn’s disease patients with IL36RN mutations
Gut Pathobiont–Derived Outer Membrane Vesicles Drive Liver Inflammation and Fibrosis in Primary Sclerosing Cholangitis–Associated Inflammatory Bowel Disease
Adipocyte autophagy limits gut inflammation by controlling oxylipin and IL‐10
Immunomodulatory Effects of New Phenanthrene Derivatives from <i>Dendrobium crumenatum</i>
Feasibility of in vivo magnetic resonance elastography of mesenteric adipose tissue in Crohn’s disease
P770 Autologous regulatory T cell transfer in patients with refractory ulcerative colitis: Interim report of a phase 1, dose-escalation trial
Activated SUMOylation restricts MHC class I antigen presentation to confer immune evasion in cancer
Store‐operated calcium entry controls innate and adaptive immune cell function in inflammatory bowel disease
Early Onset of TNFα-Driven Arthritis, Auto-inflammation, and Progressive Loss of Vision in a Patient with ALPK1 Mutation
Anti-SARS-CoV2 antibody-mediated cytokine release syndrome in a patient with acute promyelocytic leukemia
An Integrated Taxonomy for Monogenic Inflammatory Bowel Disease
Human small intestinal infection by SARS-CoV-2 is characterized by a mucosal infiltration with activated CD8+ T cells
COVID-19—from mucosal immunology to IBD patients
HDAC inhibitors promote intestinal epithelial regeneration via autocrine TGFβ1 signalling in inflammation
Multi-parameter immune profiling of peripheral blood mononuclear cells by multiplexed single-cell mass cytometry in patients with early multiple sclerosis
Leptin induces TNFα-dependent inflammation in acquired generalized lipodystrophy and combined Crohn’s disease
Environmental Microbial Factors Determine the Pattern of Inflammatory Lesions in a Murine Model of Crohn’s Disease–Like Inflammation
Adipokines and Their Role in Intestinal Inflammation
The role of adipose tissue in inflammatory bowel diseases
Oleate but not stearate induces the regulatory phenotype of myeloid suppressor cells
Store-operated Ca2+ entry regulates Ca2+-activated chloride channels and eccrine sweat gland function
Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic Cells
STIM1 controls T cell–mediated immune regulation and inflammation in chronic infection
Missense mutation in immunodeficient patients shows the multifunctional roles of coiled-coil domain 3 (CC3) in STIM1 activation