Area of research
Hematology · Biochemistry
Research interest
Research interests include Platelet Disorders and Treatments, Blood groups and transfusion, Blood transfusion and management, and Heparin-Induced Thrombocytopenia and Thrombosis.
Plasmin tames lung inflammation by redirecting immune cells.
Neutrophil-reactive autoantibodies in blood donors: Can we expect TRALI?
Antibody-mediated multicellular pathophysiology of heparin-induced thrombocytopenia and vaccine-induced thrombotic thrombocytopenia: the dynamic roles of platelets, neutrophils, endothelial cells, and monocytes.
MicroRNAs as potential architects of immune dysregulation and megakaryocytic failure in immune thrombocytopenia.
Anti-HPA-1a Fetal-Neonatal AlloImmune Thrombocytopenia: Reframing Diagnostics, Pathophysiology, and Management.
Longitudinal plasma proteomics in romiplostim-treated patients with immune thrombocytopenia.
Key features of the underlying pathophysiology of Transfusion-related acute lung injury.
The ‘Stop TPO‐RA in ITP Patients’ study: Clinical and immune modulatory effects of romiplostim tapering
The intestinal flora: The key to unraveling heterogeneity in immune thrombocytopenia?
HPA-1a antibodies in FNAIT do not distinguish αvβ3 from αIIbβ3, and bind inactive integrins more strongly than active integrins.
Inhibition of terminal complement complex formation alleviates murine antibody-mediated TRALI.
Platelet transfusion induces transfusion-associated circulatory overload in rats with myocardial infarction.
Transfusion-related acute lung injury: experimental models to study pathogenesis and therapeutic strategies.
Platelets and monocytes: A dynamic duo aiding in the prediction of the clinical response to thrombopoietin receptor agonists in immune thrombocytopenia?
Feasibility of plasma proteomics in patients with immune thrombocytopenia.
Platelet sequestration patterns and clearance rates in healthy individuals.
Increased effector memory CD4<sup>+</sup> T cells are associated with chronic childhood immune thrombocytopenia.
PF4-dependent P-selectin expression assay in comparison to the heparin-induced platelet activation assay for the diagnosis of heparin-induced thrombocytopenia.
Complement activation drives antibody-mediated transfusion-related acute lung injury via macrophage trafficking and formation of NETs.
Characterization of reverse-engineered anti-PF4 stereotypic antibodies derived from serum of patients with VITT.
Platelet TGF-β triggers immunosuppression in ITP.
Broadening the horizon of immune thrombocytopenia through Omics approaches.
Laboratory approach for vaccine-induced thrombotic thrombocytopenia diagnosis in the Netherlands.
Does anti-HPA-1a affect birthweight in fetal and neonatal alloimmune thrombocytopenia?
Developments in Transfusion Medicine: Pulmonary Transfusion Reactions and Novel Blood Cell Labeling Techniques.
The importance of disrupting complement activation in acute lung injury.
Antibodies against Platelet Glycoproteins in Clinically Suspected VITT Patients.
Fetal and neonatal alloimmune thrombocytopenia: Current pathophysiological insights and perspectives for future diagnostics and treatment.
Mechanism and intervention of murine transfusion-related acute lung injury caused by anti-CD36 antibodies