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Laurence D. Hurst

University of Bath · GB
Area of research
Molecular Biology · Genetics
Research interest
Research interests include RNA and protein synthesis mechanisms, Evolution and Genetic Dynamics, Genomics and Phylogenetic Studies, and RNA Research and Splicing.
h-index
85
citations
28,429
works
412
NIH funding
primary concept
email

Recent publications

Why do we have so many different transcripts?
PLOS Biology 2026cited by 0position: contributordoi
RID is required for both repeat-induced point mutation and nucleation of a novel transitional heterochromatic state for euchromatic repeats
Nucleic Acids Research 2025cited by 4position: middledoi
RID is required for both repeat-induced point mutation and nucleation of a novel transitional heterochromatic state for euchromatic repeats
Nucleic Acids Research 2025cited by 3position: contributordoi
Cell Compartment is a Predictor of Protein Rate of Evolution, but not in the Manner Expected: Evidence Against the Extended Complexity Hypothesis
Genome Biology and Evolution 2025cited by 1position: contributordoi
Co-option of an endogenous retrovirus (LTR7-HERVH) in early human embryogenesis: becoming useful and going unnoticed.
2025cited by 1position: contributordoi
ERV3-MLT1 provides cis-regulatory elements for human placental functioning and are commonly dysregulated in human-specific preeclampsia.
2025cited by 1position: contributordoi
Bacterial gene 5′ ends have unusual mutation rates that can mislead tests of selection
PLOS Biology 2025cited by 0position: contributordoi
Why AGG is associated with high transgene output: passenger effects and their implications for transgene design
NAR Genomics and Bioinformatics 2025cited by 0position: contributordoi
Selection on synonymous sites: the unwanted transcript hypothesis
Nature Reviews Genetics 2024cited by 22position: contributordoi
Epistasis, core-genome disharmony, and adaptation in recombining bacteria
mBio 2024cited by 14position: middledoi
Epistasis, core-genome disharmony, and adaptation in recombining bacteria
mBio 2024cited by 13position: contributordoi
Widespread allele-specific topological domains in the human genome are not confined to imprinted gene clusters.
2023cited by 26position: contributordoi
A new human embryonic cell type associated with activity of young transposable elements allows definition of the inner cell mass
PLOS Biology 2023cited by 21position: contributordoi
People with more extreme attitudes towards science have self-confidence in their understanding of science, even if this is not justified
PLOS Biology 2023cited by 20position: contributordoi
Re-evaluating evidence for adaptive mutation rate variation
Nature 2023cited by 19position: contributordoi
Both trust in, and polarization of trust in, relevant sciences have increased through the COVID-19 pandemic
PLOS ONE 2023cited by 14position: contributordoi
Staring at the onco-exaptation: the two-faced medley of an ancient retrovirus, HERVH
Journal of Clinical Investigation 2023cited by 4position: contributordoi
Genes for highly abundant proteins in Escherichia coli avoid 5’ codons that promote ribosomal initiation
PLOS Computational Biology 2023cited by 4position: contributordoi
Dynamic reprogramming of H3K9me3 at hominoid-specific retrotransposons during human preimplantation development
Cell stem cell 2022cited by 83position: middledoi
Dynamic reprogramming of H3K9me3 at hominoid-specific retrotransposons during human preimplantation development.
2022cited by 69position: contributordoi
Selfish centromeres and the wastefulness of human reproduction
PLOS Biology 2022cited by 15position: contributordoi
Stop Codon Usage as a Window into Genome Evolution: Mutation, Selection, Biased Gene Conversion and the TAG Paradox
Genome Biology and Evolution 2022cited by 11position: contributordoi
Unusual mammalian usage of TGA stop codons reveals that sequence conservation need not imply purifying selection.
2022cited by 8position: contributordoi
A Novel Gene Controls a New Structure: PiggyBac Transposable Element-Derived 1, Unique to Mammals, Controls Mammal-Specific Neuronal Paraspeckles.
2022cited by 7position: contributordoi
Evidence from Drosophila Supports Higher Duplicability of Faster Evolving Genes
Genome Biology and Evolution 2022cited by 7position: contributordoi
In rice splice variants that restore the reading frame after frameshifting indel introduction are common, often induced by the indels and sometimes lead to organism-level rescue
PLOS Genetics 2022cited by 3position: contributordoi
Transgene-design: a web application for the design of mammalian transgenes
Bioinformatics 2022cited by 2position: contributordoi
Widespread allele-specific topological domains in the human genome are not confined to imprinted gene clusters
2022cited by 1position: contributordoi
Sequence conservation need not imply purifying selection: evidence from mammalian stop codon usage
2022cited by 0position: contributordoi
Causes and Consequences of Purifying Selection on SARS-CoV-2
Genome Biology and Evolution 2021cited by 42position: contributordoi

Grants

No grants ingested yet.

Frequent collaborators

· 34 papers (2019–2026)Alexander Ho · University of Bath6 papers (2019–2023)Sihai Yang · Nanjing Agricultural University4 papers (2018–2025)Ju Huang · Nanjing Agricultural University4 papers (2018–2025)Long Wang · Shandong University3 papers (2018–2025)Dacheng Tian · Nanjing Agricultural University3 papers (2018–2021)Zsuzsanna Izsvák · University of Minnesota3 papers (2023–2024)Long Wang · Nanjing University3 papers (2022–2025)Sofia Radrizzani · 3 papers (2023–2025)Matthias Selbach · Weatherford College2 papers (2022–2025) · 2 papers (2020–2021)Zhen He · Shanxi Medical University2 papers (2020–2025)Lan Xue · Shanxi Medical University2 papers (2020–2025)Yingying Sun · Jilin University2 papers (2020–2025)Martin C. J. Maiden · University of Oxford2 papers (2021–2024)Ben Pascoe · University of Oxford2 papers (2021–2024)Samuel K. Sheppard · University of Oxford2 papers (2021–2024)Alessandro Prigione · Düsseldorf University Hospital2 papers (2019–2021)Keith A. Jolley · University of Oxford2 papers (2021–2024)David J. Kelly · University of Notre Dame2 papers (2021–2024)