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Thomas M. Roberts

University of London ·
Area of research
Molecular Biology · Genetics
Research interest
Research interests include PI3K/AKT/mTOR signaling in cancer, Virus-based gene therapy research, Polyomavirus and related diseases, and Protein Kinase Regulation and GTPase Signaling.
h-index
97
citations
38,661
works
408
NIH funding
primary concept
email

Recent publications

Genomic insights into Klebsiella pneumoniae: Virulence, resistance, and transmission in South and Southeast Asia
International Journal of Medical Microbiology 2025cited by 2position: middledoi
Genetic insights into antimicrobial resistance and virulence characteristics of Salmonella enterica isolated from Nile tilapia sourced from retail markets in Thailand
BMC Microbiology 2025cited by 1position: middledoi
Spermidine reduces peri-implant inflammation and fibrosis to nurture osseointegration
Bioactive Materials 2025cited by 1position: middledoi
PI3Kγ maintains the self-renewal of acute myeloid leukemia stem cells by regulating the pentose phosphate pathway
Blood 2024cited by 28position: middledoi
STING agonism overcomes STAT3-mediated immunosuppression and adaptive resistance to PARP inhibition in ovarian cancer
Journal for ImmunoTherapy of Cancer 2023cited by 89position: middledoi
STING agonism reprograms tumor-associated macrophages and overcomes resistance to PARP inhibition in BRCA1-deficient models of breast cancer
Nature Communications 2022cited by 242position: middledoi
TMTpro-18plex: The Expanded and Complete Set of TMTpro Reagents for Sample Multiplexing
Journal of Proteome Research 2021cited by 293position: middledoi
Extracellular | Major Sperm Protein and Sperm Locomotion
Elsevier eBooks 2021cited by 0position: middledoi
Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial
Journal of Clinical Oncology 2019cited by 153position: middledoi
Inhibition of the transcriptional kinase CDK7 overcomes therapeutic resistance in HER2-positive breast cancers
Oncogene 2019cited by 75position: middledoi
SDHC epi-mutation testing in gastrointestinal stromal tumours and related tumours in clinical practice
Scientific Reports 2019cited by 24position: middledoi
PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer
Cell Reports 2018cited by 563position: middledoi
Oridonin inhibits aberrant AKT activation in breast cancer
Oncotarget 2018cited by 21position: middledoi
CDK4/6 inhibition triggers anti-tumour immunity
Nature 2017cited by 1,513position: middledoi
The metabolic function of cyclin D3–CDK6 kinase in cancer cell survival
Nature 2017cited by 354position: middledoi
PI3K-p110α mediates the oncogenic activity induced by loss of the novel tumor suppressor PI3K-p85α
Proceedings of the National Academy of Sciences 2017cited by 106position: middledoi
Clinical and Molecular Features of Renal and Pheochromocytoma/Paraganglioma Tumor Association Syndrome (RAPTAS): Case Series and Literature Review
The Journal of Clinical Endocrinology & Metabolism 2017cited by 43position: middledoi
KRAS and YAP1 Converge to Regulate EMT and Tumor Survival
Cell 2014cited by 754position: middledoi
RETRACTED: The mTORC1/S6K1 Pathway Regulates Glutamine Metabolism through the eIF4B-Dependent Control of c-Myc Translation
Current Biology 2014cited by 266position: middledoi
An F876L Mutation in Androgen Receptor Confers Genetic and Phenotypic Resistance to MDV3100 (Enzalutamide)
Cancer Discovery 2013cited by 561position: middledoi
Major Sperm Protein and Sperm Locomotion
Encyclopedia of Biological Chemistry 2013cited by 2position: lastdoi
Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations
Nature 2012cited by 768position: middledoi
Role of Major Sperm Protein (MSP) in the Protrusion and Retraction of Ascaris Sperm
International review of cell and molecular biology 2012cited by 30position: firstdoi
Electron Tomography of MSP Filaments Derived from the Amoeboid Sperm of Ascaris Suum
Biophysical Journal 2012cited by 0position: lastdoi

Grants

Collaborative Research: A Functional Perspective on Adaptive Radiation: Explaining Differences in the Adaptive Radiations of Mainland and Island Anolis Lizards
NSF1354289$346,2542014–2018PIRePORTER
Integrated Muscle-Tendon Function in Frog Jumping
NSF0642428$396,3202007–2011PIRePORTER

Frequent collaborators

Jean J. Zhao · Broad Institute7 papers (2017–2024)Shaozhen Xie · Dana-Farber Cancer Institute5 papers (2017–2024)Qiwei Wang · Xihua University4 papers (2018–2023)Liya Ding · Fudan University3 papers (2018–2023)Ursula A. Matulonis · Harvard University3 papers (2018–2023)Panagiotis A. Konstantinopoulos · Harvard University3 papers (2018–2023) · 3 papers (2018–2023)Xueliang Gao · Medical University of South Carolina2 papers (2013–2017)Philip Smith · Cancer Research UK Cambridge Center2 papers (2017–2019)Meixiang Yang · Ministry of Education2 papers (2018–2019)Ruth Casey · Imperial College Healthcare NHS Trust2 papers (2017–2019)Taane G. Clark · London School of Hygiene & Tropical Medicine2 papers (2025–2025)Soo‐Mi Park · Cambridge University Hospitals NHS Foundation Trust2 papers (2017–2019)Eamonn R. Maher · Aston Medical (France)2 papers (2017–2019)Joyce F. Liu · Harvard University2 papers (2018–2023)Bowen Sun · Guangzhou University of Chinese Medicine2 papers (2018–2019)Eric P. Winer · Yale University2 papers (2017–2022)Katsuya Shimabukuro · Florida State University2 papers (2013–2021)Gordon J. Freeman · Harvard University2 papers (2018–2023)Steven P. Gygi · Harvard University2 papers (2017–2021)