Area of research
Pulmonary and Respiratory Medicine · Ocean Engineering
Research interest
Research topics from publications: Dysfunction of the NAc-mPFC circuit in insomnia disorder; Reduced thalamic resting‐state functional connectivity and impaired cognition in acute abstinent heroin users; Lung radiomics features for characterizing and classifying COPD stage based on feature combination strategy and multi-layer perceptron classifier; Reduced midbrain functional connectivity and recovery in abstinent heroin users; Lung Radiomics Features Selection for COPD Stage Classification Based on Auto-Metric Graph Neural Network; Acute exacerbation prediction of COPD based on Auto-metric graph neural network with inspiratory and expiratory chest CT images; Multi‐Layer Perceptron Classifier with the Proposed Combined Feature Vector of 3D CNN Features and Lung Radiomics Features for COPD Stage Classification; Longitudinal resting-state functional connectivity changes in the insular subdivisions of abstinent individuals with opioid use disorder; Abnormal hippocampal substructure volume in insomnia disorder. Representative work: BACKGROUND: Insomnia disorder (ID) is a prevalent sleep disorder, which seriously affects people's daily life and was found to be associated with increased frequency of sleep stage shifts. Previous findings had revealed the critical role of the nucleus accumbens (NAc) in sleep-wake transition. However, the neuroimaging studies of the NAc in patients with ID have been rare. We hypothesized that structural and functional abnormalities of the NAc would be implicated in ID. METHODS: Twenty-six ID patients and 36 matched healthy controls (HC) were included in the current study. The volumes and corresponding resting-state functional connectivity (RSFC) of the bilateral NAc were compared between th As a critical component of cortico-striato-thalamo-cortical loop in addiction, our understanding of the thalamus in impaired cognition of heroin users (HU) has been limited. Due to the complex thalamic connection with cortical and subcortical regions, thalamus was divided into prefrontal (PFC), occipital (OC), premotor, primary motor, sensory, temporal, and posterior parietal association subregions according to white matter tractography. We adopted seven subregions of bilateral thalamus as regions of interest to systematically study the implications of distinct thalamic nuclei in acute abstinent HU. The volume and resting-state functional connecti
Acute exacerbation prediction of COPD based on Auto-metric graph neural network with inspiratory and expiratory chest CT images
Multi‐Layer Perceptron Classifier with the Proposed Combined Feature Vector of 3D CNN Features and Lung Radiomics Features for COPD Stage Classification
Lung radiomics features for characterizing and classifying COPD stage based on feature combination strategy and multi-layer perceptron classifier
Lung Radiomics Features Selection for COPD Stage Classification Based on Auto-Metric Graph Neural Network
Longitudinal resting-state functional connectivity changes in the insular subdivisions of abstinent individuals with opioid use disorder
Reduced thalamic resting‐state functional connectivity and impaired cognition in acute abstinent heroin users
Reduced midbrain functional connectivity and recovery in abstinent heroin users
Abnormal hippocampal substructure volume in insomnia disorder
Dysfunction of the NAc-mPFC circuit in insomnia disorder