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José Á. García-Sáenz

Columbia University · ES
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Area of research
Oncology · Cancer Research
Research interest
Research interests include Advanced Breast Cancer Therapies, Breast Cancer Treatment Studies, Cancer Treatment and Pharmacology, and HER2/EGFR in Cancer Research.
h-index
51
citations
14,491
works
516
NIH funding
primary concept
Medicine
email

Recent publications

Final survival results from the PENELOPE-B trial investigating palbociclib versus placebo for patients with high-risk HR+/HER2− breast cancer and residual disease after neoadjuvant chemotherapy
Annals of Oncology 2025cited by 17position: middledoi
Clinical Validity of Repeated Circulating Tumor Cell Enumeration as an Early Treatment Monitoring Tool for Metastatic Breast Cancer in the PREDICT Global Pooled Analysis
Clinical Cancer Research 2025cited by 12position: middledoi
Lessons learned from a candidate gene study investigating aromatase inhibitor treatment outcome in breast cancer
npj Breast Cancer 2025cited by 1position: middledoi
Elacestrant in ER+, HER2− Metastatic Breast Cancer with <i>ESR1</i> -Mutated Tumors: Subgroup Analyses from the Phase III EMERALD Trial by Prior Duration of Endocrine Therapy plus CDK4/6 Inhibitor and in Clinical Subgroups
Clinical Cancer Research 2024cited by 79position: middledoi
Understanding the genetic complexity of puberty timing across the allele frequency spectrum
Nature Genetics 2024cited by 44position: middledoi
High Mechanical Conditioning by Tumor Extracellular Matrix Stiffness Is a Predictive Biomarker for Antifibrotic Therapy in HER2-Negative Breast Cancer
Clinical Cancer Research 2024cited by 14position: middledoi
Imlunestrant, an oral selective estrogen receptor degrader, as monotherapy and combined with abemaciclib, in recurrent/advanced ER-positive endometrioid endometrial cancer: Results from the phase 1a/1b EMBER study
Gynecologic Oncology 2024cited by 9position: middledoi
Publisher Correction: Understanding the genetic complexity of puberty timing across the allele frequency spectrum
Nature Genetics 2024cited by 3position: middledoi
414P The complex relationship between circulating tumor cells (CTCs) and brain metastases (BMs) in metastatic breast cancer (mBC): A retrospective pooled analysis
Annals of Oncology 2024cited by 1position: middledoi
Neratinib + fulvestrant + trastuzumab for HR-positive, HER2-negative, HER2-mutant metastatic breast cancer: outcomes and biomarker analysis from the SUMMIT trial
Annals of Oncology 2023cited by 58position: middledoi
Associations of a Breast Cancer Polygenic Risk Score With Tumor Characteristics and Survival
Journal of Clinical Oncology 2023cited by 26position: middledoi
Association of the <scp> <i>CHEK2</i> </scp> c. <scp>1100delC</scp> variant, radiotherapy, and systemic treatment with contralateral breast cancer risk and breast cancer‐specific survival
Cancer Medicine 2023cited by 10position: middledoi
A Likelihood Ratio Approach for Utilizing Case-Control Data in the Clinical Classification of Rare Sequence Variants: Application to BRCA1 and BRCA2
Human Mutation 2023cited by 6position: middledoi
Evaluation of European-based polygenic risk score for breast cancer in Ashkenazi Jewish women in Israel
Journal of Medical Genetics 2023cited by 5position: middledoi
Understanding the genetic complexity of puberty timing across the allele frequency spectrum
medRxiv 2023cited by 5position: middledoi
Elacestrant (oral selective estrogen receptor degrader) Versus Standard Endocrine Therapy for Estrogen Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Advanced Breast Cancer: Results From the Randomized Phase III EMERALD Trial
Journal of Clinical Oncology 2022cited by 676position: middledoi
Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study
British Journal of Sports Medicine 2022cited by 96position: middledoi
Common variants in breast cancer risk loci predispose to distinct tumor subtypes
Breast Cancer Research 2022cited by 31position: middledoi
Incorporating progesterone receptor expression into the PREDICT breast prognostic model
European Journal of Cancer 2022cited by 24position: middledoi
Treatment With Etirinotecan Pegol for Patients With Metastatic Breast Cancer and Brain Metastases
JAMA Oncology 2022cited by 23position: middledoi
Modeling the Prognostic Impact of Circulating Tumor Cells Enumeration in Metastatic Breast Cancer for Clinical Trial Design Simulation
The Oncologist 2022cited by 12position: middledoi
Breast Cancer Risk Factors and Survival by Tumor Subtype: Pooled Analyses from the Breast Cancer Association Consortium
Cancer Epidemiology Biomarkers & Prevention 2021cited by 40position: middledoi
Mendelian randomisation study of smoking exposure in relation to breast cancer risk
British Journal of Cancer 2021cited by 22position: middledoi
Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment
Breast Cancer Research 2021cited by 22position: middledoi
Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element
The American Journal of Human Genetics 2021cited by 12position: middledoi
Common variants in breast cancer risk loci predispose to distinct tumor subtypes.
Apollo (University of Cambridge) 2021cited by 6position: middledoi
Abstract GS4-08: Clinical utility of repeated circulating tumor cell (CTC) enumeration as early treatment monitoring tool in metastatic breast cancer (MBC) - a global pooled analysis with individual patient data
Cancer Research 2021cited by 5position: middledoi
Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis
Scientific Reports 2021cited by 4position: middledoi
Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses
Nature Genetics 2020cited by 562position: middledoi
Management of Abemaciclib-Associated Adverse Events in Patients with Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: Safety Analysis of MONARCH 2 and MONARCH 3
The Oncologist 2020cited by 169position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Javier Cortés · Universidade Nova de Lisboa2 papers (2024–2024)Noelia Martínez-Jáñez · Instituto Cajal2 papers (2019–2024)Miguel Martín · Spanish Ovarian Cancer Research Group2 papers (2019–2025)François‐Clément Bidard · Inserm2 papers (2024–2024)Antonio Llombart‐Cussac · MedSIR (Spain)1 papers (2024–2024)Joohyuk Sohn · Fudan University Shanghai Cancer Center1 papers (2020–2020)Salvatore Siena · Metropolitana Milanese (Italy)1 papers (2012–2012)Janice Lu · Northwestern University1 papers (2024–2024) · 1 papers (2024–2024)Aditya Bardia · Comprehensive Blood & Cancer Center1 papers (2024–2024) · 1 papers (2024–2024)Emilio Alba · Universidad de Málaga1 papers (2024–2024)Ann H. Partridge · Harvard University1 papers (2019–2019)Eva Carrasco · Breast International Group1 papers (2019–2019)Juan de la Haba-Rodríguez · Instituto Maimónides de Investigación Biomédica de Córdoba1 papers (2019–2019)Don S. Dizon · Worldwide Clinical Trials (United States)1 papers (2024–2024)Bahriye Aktas · Universität Trier1 papers (2019–2019)Fernando Moreno · Tufts University1 papers (2024–2024) · 1 papers (2024–2024)Luís Manso · Universitair Ziekenhuis Leuven1 papers (2024–2024)
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