Area of research
Computational Theory and Mathematics · Physiology
Research interest
Research interests include Medicine, Computational biology, Pharmacology, Drug discovery, Systems pharmacology, and Mechanism (biology).
ADMETPred: a high-throughput ADMET prediction platform integrating multi-model algorithms and interpretable substructure identification
Caffeic acid ameliorates D-galactose-induced brain senescence via the BHMT/NMDAR/CREB axis
Orlistat targets NEDD8 conjugating enzyme UBC12 for cancer therapy
Ginsenoside Ro ameliorates cognitive impairment and neuroinflammation in APP/PS1 mice via the IBA1/GFAP-MAPK signaling pathway
Exploring the Therapeutic Mechanism of Xinbao Pill in Brain Injury After Cardiopulmonary Resuscitation Based on Network Pharmacology, Metabolomics, and Experimental Verification
Yangxue Qingnao Wan ameliorates cognitive impairment in scopolamine-induced AD mice via modulating neuropeptide signaling pathways and suppressing neuroinflammation
Pharmacovigilance analysis of vision disorders relating to brimonidine treatment and mechanism study using network toxicology and molecular docking
3-Hydroxybutyrate, a metabolite in sustaining neuronal cell vitality: a mendelian randomization and in vitro experimentation
Yangxue Qingnao Wan Ameliorates Cognitive Impairment in Scopolamine-Induced Ad Mice Via Modulating Neuropeptide Signaling Pathways and Suppressing Neuroinflammation
Integrative multi-omics approach for drug repositioning in Alzheimer's disease
Photocatalytic [4 + 2] Annulation Reaction of Amine and Olefin Mediated by Benzophenone for Tetrahydroquinoline Synthesis
SZBC-AI4TCM: a comprehensive web-based computing platform for traditional Chinese medicine research and development
Quercetagitrin Targets EIF3D to Activate NCOA4-Mediated Ferritinophagy-Dependent Ferroptosis for the Treatment of Non-Small Cell Lung Cancer
Network Medicine: A Potential Approach for Virtual Drug Screening
Unveiling the molecular mechanisms of Danggui-Shaoyao-San against Alzheimer’s disease in APP/PS1 mice via integrating proteomic and metabolomic approaches
Advanced Mass-Spectra-Based Machine Learning for Predicting the Toxicity of Traditional Chinese Medicines
Network Medicine‐Based Strategy Identifies Maprotiline as a Repurposable Drug by Inhibiting PD‐L1 Expression via Targeting SPOP in Cancer
The potential therapeutic strategy in combating neurodegenerative diseases: Focusing on natural products
TarKG: a comprehensive biomedical knowledge graph for target discovery
Photocatalytic α-aminoalkyl radical addition of amines mediated by benzophenone under visible light
An endophenotype network strategy uncovers YangXue QingNao Wan suppresses Aβ deposition, improves mitochondrial dysfunction and glucose metabolism
Neuroinflammation inhibition and neuroprotective effects of purpurin, a potential anti‐AD compound, screened via network proximity and gene enrichment analyses
3DSTarPred: A Web Server for Target Prediction of Bioactive Small Molecules Based on 3D Shape Similarity
Associations of dichlorophenols, trichlorophenols, and ortho-phenylphenol with the risk and prognosis of diabetes and prediabetes: A population-based study
[Chemical components and in vitro anti-aging activity of Yangxue Qingnao Wan based on UPLC-Q-TOF-MS/MS].
Network Medicine Approach Unravels Endophenotype Signature in Alzheimer’s Disease through Large-Scale Comparative Proteomics Analysis: Vascular Dysfunction as a Prime Example
Corrigendum to “Associations of dichlorophenols, trichlorophenols, and ortho-phenylphenol with the risk and prognosis of diabetes and prediabetes: A population-based study” [Ecotoxicol. Environ. Saf. 277 (2024) 116345]
3-Hydroxybutyrate, A Metabolite in Sustaining Neuronal Cell Vitality: A Mendelian Randomization and in Vitro Experimentation
Exploring pharmacological active ingredients of traditional Chinese medicine by pharmacotranscriptomic map in ITCM
Inflammatory microenvironment in gastric premalignant lesions: implication and application