Area of research
Epidemiology · Hepatology
Research interest
Research interests include Hepatitis B Virus Studies, Hepatitis C virus research, SARS-CoV-2 and COVID-19 Research, and Liver Disease Diagnosis and Treatment.
Acetyl-coenzyme A synthetase 2-mediated acetyl-coenzyme A accumulation promotes mitophagy and tumor growth via increased H3K27ac in hepatitis B virus-related hepatocellular carcinoma
Phosphoglycerate dehydrogenase stabilizes protein kinase C delta type mRNA to promote hepatocellular carcinoma progression.
GFAT1 promotes the progression of hepatocellular carcinoma via enhancing the O-GlcNAcylation of VEZF1.
Rapavir, a novel inhibitor of sodium taurocholate cotransporting polypeptide, potently blocks hepatitis B virus entry.
PCK1 deficiency promotes MASH-HCC progression by 12-HETE-induced CD8<sup>+</sup> T cell dysfunction.
Developing an Accurate Assay for Detection of Serum HBV RNA and SP1 Variant in CHB Based on Long-Read Sequencing.
Tenofovir to Prevent HIV Infection in Western China: Pragmatic Randomized Controlled Trial.
Loss of SLC27A5 Activates Hepatic Stellate Cells and Promotes Liver Fibrosis via Unconjugated Cholic Acid.
Affinity molecular assay for detecting Candida albicans using chitin affinity and RPA-CRISPR/Cas12a.
SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia.
Detection of HBV DNA integration in plasma cell-free DNA of different HBV diseases utilizing DNA capture strategy.
Prophylactic efficacy of an intranasal spray with 2 synergetic antibodies neutralizing Omicron
Prophylactic efficacy of an intranasal spray with 2 synergetic antibodies neutralizing Omicron
Identification of virus epitopes and reactive T-cell receptors from memory T cells without peptide synthesis.
Communication between small cytosolic dsDNA and autophagy inhibits CGAS (cyclic GMP-AMP synthase) activation.
O-GlcNAcylation of YTHDF2 promotes HBV-related hepatocellular carcinoma progression in an N<sup>6</sup>-methyladenosine-dependent manner.
Deficiency of gluconeogenic enzyme PCK1 promotes metabolic-associated fatty liver disease through PI3K/AKT/PDGF axis activation in male mice.
High dietary fructose promotes hepatocellular carcinoma progression by enhancing O-GlcNAcylation via microbiota-derived acetate.
Gluconeogenic enzyme PCK1 supports S-adenosylmethionine biosynthesis and promotes H3K9me3 modification to suppress hepatocellular carcinoma progression.
Bivalent intra-spike binding provides durability against emergent Omicron lineages: Results from a global consortium
O-GlcNAcylation of SPOP promotes carcinogenesis in hepatocellular carcinoma.
Real-world effectiveness of an intranasal spray A8G6 antibody cocktail in the post-exposure prophylaxis of COVID-19.
Hepatitis B virus promotes its own replication by enhancing RAB5A-mediated dual activation of endosomal and autophagic vesicle pathways.
Increased immune escape of the new SARS-CoV-2 variant of concern Omicron.
Structures of Omicron spike complexes and implications for neutralizing antibody development
Structures of Omicron spike complexes and implications for neutralizing antibody development
Characterization of SARS-CoV-2-specific humoral immunity and its potential applications and therapeutic prospects.
APOE interacts with ACE2 inhibiting SARS-CoV-2 cellular entry and inflammation in COVID-19 patients.
Characterization of SARS-CoV-2 Variants B.1.617.1 (Kappa), B.1.617.2 (Delta), and B.1.618 by Cell Entry and Immune Evasion
A potent neutralizing antibody provides protection against SARS-CoV-2 Omicron and Delta variants via nasal delivery.