Ophry Pines

Biogenesis and function of the mitochondrial solute carrier (SLC25) family in yeast

Mitochondrial derived vesicles‐ Quo Vadis?

Privileged proteins with a second residence: dual targeting and conditional re‐routing of mitochondrial proteins

Mitochondrial‐derived vesicles retain membrane potential and contain a functional ATP synthase

Systematic Approaches to Study Eclipsed Targeting of Proteins Uncover a New Family of Mitochondrial Proteins

Ubiquitination Occurs in the Mitochondrial Matrix by Eclipsed Targeted Components of the Ubiquitination Machinery

Depletion of Fumarate Hydratase, an Essential TCA Cycle Enzyme, Drives Proliferation in a Two-Step Model

A combination of Class-I fumarases and metabolites (α-ketoglutarate and fumarate) signal the DNA damage response in <i>Escherichia coli</i>

Fumarase affects the deoxyribonucleic acid damage response by protecting the mitochondrial desulfurase Nfs1p from modification and inactivation

Haploinsufficiency due to a novel ACO2 deletion causes mitochondrial dysfunction in fibroblasts from a patient with dominant optic nerve atrophy

Post-translational Modifications of Fumarase Regulate its Enzyme Activity and Function in Respiration and the DNA Damage Response

A combination of two novel VARS2 variants causes a mitochondrial disorder associated with failure to thrive and pulmonary hypertension

Genome-wide SWAp-Tag yeast libraries for proteome exploration

Fumarase: From the TCA Cycle to DNA Damage Response and Tumor Suppression

Yeast aconitase mitochondrial import is modulated by interactions of its C and N terminal domains and Ssa1/2 (Hsp70)

Homozygous mutation, p.Pro304His, in IDH3A, encoding isocitrate dehydrogenase subunit is associated with severe encephalopathy in infancy

Fumarase is involved in DNA double-strand break resection through a functional interaction with Sae2

Bacterial fumarase and L-malic acid are evolutionary ancient components of the DNA damage response

Detection of Dual Targeting and Dual Function of Mitochondrial Proteins in Yeast

Human Fumarate Hydratase Is Dual Localized by an Alternative Transcription Initiation Mechanism

Cytosolic Hsp60 Can Modulate Proteasome Activity in Yeast

Dual-Targeted Proteins Tend to be More Evolutionarily Conserved

Protein folding as a driving force for dual protein targeting in eukaryotes

Agenesis of corpus callosum and optic nerve hypoplasia due to mutations in <i>SLC25A1</i> encoding the mitochondrial citrate transporter

Evolving Dual Targeting of a Prokaryotic Protein in Yeast

Infantile Cerebellar-Retinal Degeneration Associated with a Mutation in Mitochondrial Aconitase, ACO2

Study of <i>LPIN1</i>, <i>LPIN2</i> and <i>LPIN3</i> in rhabdomyolysis and exercise‐induced myalgia