Area of research
Molecular Biology · Physiology
Research interest
Research interests include Mitochondrial Function and Pathology, Adipose Tissue and Metabolism, Cancer, Hypoxia, and Metabolism, and Metabolism and Genetic Disorders.
Disrupted energy metabolism is associated with retinal ganglion cell degeneration in autosomal dominant optic atrophy
A human brain map of mitochondrial respiratory capacity and diversity
Impaired AMPK control of alveolar epithelial cell metabolism promotes pulmonary fibrosis
TRAF6 integrates innate immune signals to regulate glucose homeostasis via Parkin-dependent and Parkin-independent mitophagy
Acidic Nanoparticles Restore Lysosomal Acidification and Rescue Metabolic Dysfunction in Pancreatic β-Cells under Lipotoxic Conditions
Mitochondrial morphology controls fatty acid utilization by changing <scp>CPT1</scp> sensitivity to <scp>malonyl‐CoA</scp>
Spatial mapping of mitochondrial networks and bioenergetics in lung cancer
Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease
Calculation of ATP production rates using the Seahorse XF Analyzer
Inhibition of <scp>ATP</scp> synthase reverse activity restores energy homeostasis in mitochondrial pathologies
Glucose Deprivation Promotes Pseudohypoxia and Dedifferentiation in Lung Adenocarcinoma
MYC is a regulator of androgen receptor inhibition-induced metabolic requirements in prostate cancer
Mitochondrial signal transduction
The mitochondrial fission protein Drp1 in liver is required to mitigate NASH and prevents the activation of the mitochondrial ISR
Parkin regulates adiposity by coordinating mitophagy with mitochondrial biogenesis in white adipocytes
Ciliary neurotrophic factor-mediated neuroprotection involves enhanced glycolysis and anabolism in degenerating mouse retinas
TNFα-Induced Oxidative Stress and Mitochondrial Dysfunction Alter Hypothalamic Neurogenesis and Promote Appetite Versus Satiety Neuropeptide Expression in Mice
IRGM1 links mitochondrial quality control to autoimmunity
Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease
ATP-consuming futile cycles as energy dissipating mechanisms to counteract obesity
DLST-dependence dictates metabolic heterogeneity in TCA-cycle usage among triple-negative breast cancer
Recruitment and remodeling of peridroplet mitochondria in human adipose tissue
A novel approach to measure mitochondrial respiration in frozen biological samples
Cristae undergo continuous cycles of membrane remodelling in a MICOS‐dependent manner
Estrogen receptor α controls metabolism in white and brown adipocytes by regulating <i>Polg1</i> and mitochondrial remodeling
Mitochondrial oxidative function in NAFLD: Friend or foe?
Fgr kinase is required for proinflammatory macrophage activation during diet-induced obesity
Measuring Mitochondrial Respiration in Previously Frozen Biological Samples
The biology of lipid droplet-bound mitochondria
Modulating lysosomal pH: a molecular and nanoscale materials design perspective