Area of research
Cancer Research · Pulmonary and Respiratory Medicine
Research interest
Research interests include Cancer Genomics and Diagnostics, Lung Cancer Treatments and Mutations, Neuroblastoma Research and Treatments, and Cancer Research and Treatments.
Extrachromosomal DNA–Driven Oncogene Dosage Heterogeneity Promotes Rapid Adaptation to Therapy in <i>MYCN</i> -Amplified Cancers
Targeting MYCN upregulates L1CAM tumor antigen in MYCN-dysregulated neuroblastoma to increase CAR T cell efficacy
Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells
Defining the landscape of circular RNAs in neuroblastoma unveils a global suppressive function of MYCN
Therapeutic targeting of ATR in alveolar rhabdomyosarcoma
ecDNA hubs drive cooperative intermolecular oncogene expression
Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma
Publisher Correction: Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma
Exploiting a PAX3-FOXO1-induced synthetic lethal ATR dependency for rhabdomyosarcoma therapy
Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma
Enhancer hijacking determines intra- and extrachromosomal circular <i>MYCN</i> amplicon architecture in neuroblastoma