Area of research
Cell Biology · Atomic and Molecular Physics, and Optics
Research interest
Research interests include Biology, Chemistry, Cell biology, Biophysics, DNA, and Vinculin.
PIEZO1-mediated calcium signaling reinforces mechanical properties of hair follicle stem cells to promote quiescence
Alternative molecular mechanisms for force transmission at adherens junctions via β-catenin-vinculin interaction
The focal adhesion protein talin is a mechanically gated A-kinase anchoring protein
Actin polymerisation and crosslinking drive left-right asymmetry in single cell and cell collectives
Unveiling Mechanical Activation: GAIN Domain Unfolding and Dissociation in Adhesion GPCRs
Application of piconewton forces to individual filopodia reveals mechanosensory role of L-type Ca2+ channels
Modulating binding affinity, specificity, and configurations by multivalent interactions
Force-Dependent Interactions between Talin and Full-Length Vinculin
Talin mechanosensitivity is modulated by a direct interaction with cyclin-dependent kinase-1
Mechanical instability of adherens junctions overrides intrinsic quiescence of hair follicle stem cells
Myosin IIA and formin dependent mechanosensitivity of filopodia adhesion
Direct single-molecule quantification reveals unexpectedly high mechanical stability of vinculin—talin/α-catenin linkages
Force-Dependent Binding Constants
Force-Dependent Regulation of Talin–KANK1 Complex at Focal Adhesions
Folding/unfolding kinetics of G-quadruplexes upstream of the P1 promoter of the human BCL-2 oncogene
Talin as a mechanosensitive signaling hub
Functions of FACT in Breaking the Nucleosome and Maintaining Its Integrity at the Single-Nucleosome Level
Dystrophin As a Molecular Shock Absorber
Effects of Mechanical Stimuli on Profilin- and Formin-Mediated Actin Polymerization
A single molecule analysis of H-NS uncouples DNA binding affinity from DNA specificity
Tension-Dependent Stretching Activates ZO-1 to Control the Junctional Localization of Its Interactors
The spatial organization of intra-tumour heterogeneity and evolutionary trajectories of metastases in hepatocellular carcinoma
Non-canonical activation of OmpR drives acid and osmotic stress responses in single bacterial cells
Force-dependent binding of vinculin to α-catenin regulates cell–cell contact stability and collective cell behavior
mDia1 senses both force and torque during F-actin filament polymerization
Mechanotransmission and Mechanosensing of Human alpha-Actinin 1
Charged residues in the H-NS linker drive DNA binding and gene silencing in single cells
Elasticity of the Transition State Leading to an Unexpected Mechanical Stabilization of Titin Immunoglobulin Domains
Studying the mechanical responses of proteins using magnetic tweezers
The mechanical response of talin