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John D. Helmann

Cornell University · US
Area of research
Genetics · Molecular Biology
Research interest
Research interests include Bacterial Genetics and Biotechnology, RNA and protein synthesis mechanisms, Bacteriophages and microbial interactions, and Trace Elements in Health.
h-index
95
citations
26,602
works
327
NIH funding
primary concept
email

Recent publications

Metals in Motion: Understanding Labile Metal Pools in Bacteria
Biochemistry 2025cited by 34position: firstdoi
Microbial metal physiology: ions to ecosystems
Nature Reviews Microbiology 2025cited by 16position: firstdoi
The extracytoplasmic sigma factor σX supports biofilm formation and increases biocontrol efficacy in Bacillus velezensis 118
Scientific Reports 2025cited by 4position: lastdoi
The elements of life: A biocentric tour of the periodic table
Advances in microbial physiology/Advances in Microbial Physiology 2023cited by 65position: lastdoi
Meddling with Metal Sensors: Fur-Family Proteins as Signaling Hubs
Journal of Bacteriology 2023cited by 46position: lastdoi
Mutations in <i>rpoB</i> That Confer Rifampicin Resistance Can Alter Levels of Peptidoglycan Precursors and Affect β-Lactam Susceptibility
mBio 2023cited by 45position: lastdoi
A model industrial workhorse: <i>Bacillus subtilis</i> strain 168 and its genome after a quarter of a century
Microbial Biotechnology 2023cited by 38position: middledoi
A Central Role for Magnesium Homeostasis during Adaptation to Osmotic Stress
mBio 2022cited by 54position: lastdoi
Mini Review: Bacterial Membrane Composition and Its Modulation in Response to Stress
Frontiers in Molecular Biosciences 2021cited by 130position: lastdoi
Dysregulation of Magnesium Transport Protects Bacillus subtilis against Manganese and Cobalt Intoxication
Journal of Bacteriology 2020cited by 38position: lastdoi
Where to begin? Sigma factors and the selectivity of transcription initiation in bacteria
Molecular Microbiology 2019cited by 84position: firstdoi
<i>Bacillus subtilis</i> FolE is sustained by the ZagA zinc metallochaperone and the alarmone ZTP under conditions of zinc deficiency
Molecular Microbiology 2019cited by 75position: lastdoi
Antagonism of Two Plant-Growth Promoting Bacillus velezensis Isolates Against Ralstonia solanacearum and Fusarium oxysporum
Scientific Reports 2018cited by 363position: middledoi
A metabolic checkpoint protein GlmR is important for diverting carbon into peptidoglycan biosynthesis in Bacillus subtilis
PLoS Genetics 2018cited by 49position: lastdoi
Metal homeostasis and resistance in bacteria
Nature Reviews Microbiology 2017cited by 781position: lastdoi
The Role of Bacillithiol in Gram-Positive <i>Firmicutes</i>
Antioxidants and Redox Signaling 2017cited by 120position: lastdoi
Sequential induction of Fur-regulated genes in response to iron limitation in <i>Bacillus subtilis</i>
Proceedings of the National Academy of Sciences 2017cited by 112position: lastdoi
Don’t let sleeping dogmas lie: new views of peptidoglycan synthesis and its regulation
Molecular Microbiology 2017cited by 97position: middledoi
Ferrous iron efflux systems in bacteria
Metallomics 2017cited by 95position: lastdoi
Redox Sensing by Fe <sup>2+</sup> in Bacterial Fur Family Metalloregulators
Antioxidants and Redox Signaling 2017cited by 82position: lastdoi
Bacillus subtilis extracytoplasmic function (ECF) sigma factors and defense of the cell envelope
Current Opinion in Microbiology 2016cited by 138position: firstdoi
<i>Bacillus subtilis</i> MntR coordinates the transcriptional regulation of manganese uptake and efflux systems
Molecular Microbiology 2016cited by 93position: lastdoi
Molecular logic of the Zur-regulated zinc deprivation response in Bacillus subtilis
Nature Communications 2016cited by 90position: lastdoi
Depletion of Undecaprenyl Pyrophosphate Phosphatases Disrupts Cell Envelope Biogenesis in Bacillus subtilis
Journal of Bacteriology 2016cited by 73position: lastdoi
Lack of formylated methionyl-tRNA has pleiotropic effects on Bacillus subtilis
Microbiology 2016cited by 19position: lastdoi
Mn2+-Sensing Mechanisms of yybP-ykoY Orphan Riboswitches
Molecular Cell 2015cited by 138position: middledoi
Concentration- and chromosome-organization-dependent regulator unbinding from DNA for transcription regulation in living cells
Nature Communications 2015cited by 102position: middledoi
<scp>PfeT</scp>, a <scp>P</scp><sub>1B4</sub>‐type <scp>ATP</scp>ase, effluxes ferrous iron and protects <scp><i>B</i></scp><i>acillus subtilis</i> against iron intoxication
Molecular Microbiology 2015cited by 94position: lastdoi
Specificity of Metal Sensing: Iron and Manganese Homeostasis in Bacillus subtilis
Journal of Biological Chemistry 2014cited by 160position: firstdoi
Bacillithiol is a major buffer of the labile zinc pool in <scp><i>B</i></scp><i>acillus subtilis</i>
Molecular Microbiology 2014cited by 96position: lastdoi

Grants

Bacillithiol and the Redox Biology of Bacillus Subtilis
NSF1020481$629,3322010–2014PIRePORTER
Gene Regulation by Oxidative Stress in Bacillus subtilis
NSF0640616$390,0002007–2009PIRePORTER
Gene Regulation by Oxidative Stress in Bacillus Subtilis
NSF0235255$315,0002003–2006PIRePORTER
Selective Gene Regulation by Manganese and Iron in Bacillus subtilis
NSF9983656$315,0002000–2003PIRePORTER
Regulation of Zinc Homeostasis in Bacillus subtilis
NSF9905682$270,0001999–2003PIRePORTER
Selective Gene Regulation by Manganese and Iron in Bacillus subtilis
NSF9630411$315,0001997–1999PIRePORTER
Selective Gene Regulation by Manganese and Iron in Bacillus subtilis
NSF9317425$285,0001994–1996PIRePORTER

Frequent collaborators

Ahmed Gaballa · Cornell University9 papers (2012–2025)Pete Chandrangsu · Scripps College7 papers (2013–2019)Hualiang Pi · Vanderbilt University6 papers (2017–2025)Yanfei Cai · South China Agricultural University3 papers (2016–2025)Azul Pinochet‐Barros · Cornell University3 papers (2015–2017)Jung‐Ho Shin · Chonnam National University2 papers (2016–2016)Brian M. Wendel · Cornell University2 papers (2020–2022)Tai‐Yen Chen · University of Houston2 papers (2012–2015) · 2 papers (2014–2016)Peng Chen · Zhejiang University2 papers (2012–2015)Heng Zhao · Fujian Normal University2 papers (2016–2017)Xiaojuan Huang · University of Science and Technology of China2 papers (2016–2019)Vaidehi Patel · National Institute of Standards and Technology2 papers (2017–2018)Danya J. Martell · Broad Institute2 papers (2012–2015)Haike Antelmann · Freie Universität Berlin2 papers (2012–2017)Ian R. Price · Evotec (United States)1 papers (2015–2015) · 1 papers (2023–2023)Hanqin Xiong · South China Agricultural University1 papers (2018–2018)Ace George Santiago · Harvard University1 papers (2015–2015)Roman Dziarski · Indiana University School of Medicine1 papers (2014–2014)