Area of research
Cancer Research · Oncology
Research interest
Research interests include Protease and Inhibitor Mechanisms, Peptidase Inhibition and Analysis, Cell Adhesion Molecules Research, and RNA and protein synthesis mechanisms.
Biselective remodeling of the melanoma tumor microenvironment prevents metastasis and enhances immune activation in mouse models.
Persistent ECM Scarring Reprograms Intestinal Stem Cells to Drive Chronic Inflammation
Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior.
Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer
Recycled melanoma-secreted melanosomes regulate tumor-associated macrophage diversification
Redefining metalloproteases specificity through network proteolysis.
Mirror‐Image Random Nonstandard Peptides Integrated Discovery (MI‐RaPID) Technology Yields Highly Stable and Selective Macrocyclic Peptide Inhibitors for Matrix Metallopeptidase 7
Targeting Tumor-Associated Sialic Acids Using Chimeric Switch Receptors Based on Siglec-9 Enhances the Antitumor Efficacy of Engineered T Cells.
Enhancing uterine receptivity for embryo implantation through controlled collagenase intervention.
Proteolytic Vesicles Derived from <i>Salmonella enterica</i> Serovar Typhimurium-Infected Macrophages: Enhancing MMP-9-Mediated Invasion and EV Accumulation.
Figure S3 from Targeting Tumor-Associated Sialic Acids Using Chimeric Switch Receptors Based on Siglec-9 Enhances the Antitumor Efficacy of Engineered T Cells
Data from Targeting Tumor-Associated Sialic Acids Using Chimeric Switch Receptors Based on Siglec-9 Enhances the Antitumor Efficacy of Engineered T Cells
Figure S2 from Targeting Tumor-Associated Sialic Acids Using Chimeric Switch Receptors Based on Siglec-9 Enhances the Antitumor Efficacy of Engineered T Cells
Figure S4 from Targeting Tumor-Associated Sialic Acids Using Chimeric Switch Receptors Based on Siglec-9 Enhances the Antitumor Efficacy of Engineered T Cells
Figure S1 from Targeting Tumor-Associated Sialic Acids Using Chimeric Switch Receptors Based on Siglec-9 Enhances the Antitumor Efficacy of Engineered T Cells
Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson’s disease patients
Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis.
Blockade of the protease ADAM17 ameliorates experimental pancreatitis.
Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers
Nonuniformity in Periodontal Ligament: Mechanics and Matrix Composition
Differential tissue stiffness of body column facilitates locomotion of <i>Hydra</i> on solid substrates.
Differential tissue stiffness of body column facilitates locomotion of <i>Hydra</i> on solid substrates
MMP9 modulates the metastatic cascade and immune landscape for breast cancer anti-metastatic therapy
Persistent Chemiluminescent Glow of Phenoxy-dioxetane Luminophore Enables Unique CRET-Based Detection of Proteases.
The extracellular matrix protein agrin promotes heart regeneration in mice
Development of High Affinity and High Specificity Inhibitors of Matrix Metalloproteinase 14 through Computational Design and Directed Evolution
PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells
The Functional Maturation of A Disintegrin and Metalloproteinase (ADAM) 9, 10, and 17 Requires Processing at a Newly Identified Proprotein Convertase (PC) Cleavage Site
Cytokine secretion and NK cell activity in human ADAM17 deficiency
Affinity- and Specificity-Enhancing Mutations Are Frequent in Multispecific Interactions between TIMP2 and MMPs