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Daniel J. Sheward

Karolinska Institutet · SE
Area of research
Infectious Diseases · Virology
Research interest
Research interests include SARS-CoV-2 and COVID-19 Research, HIV Research and Treatment, HIV/AIDS drug development and treatment, and Monoclonal and Polyclonal Antibodies Research.
h-index
29
citations
5,134
works
104
NIH funding
primary concept
Biology
email

Recent publications

Generation of antigen-specific paired-chain antibodies using large language models
Cell 2025cited by 11position: middledoi
Humoral immune responses to the monovalent XBB.1.5-adapted BNT162b2 mRNA booster in Sweden
The Lancet Infectious Diseases 2024cited by 32position: middledoi
Structural basis of broad SARS-CoV-2 cross-neutralization by affinity-matured public antibodies
Cell Reports Medicine 2024cited by 30position: firstdoi
Three immunizations with Novavax’s protein vaccines increase antibody breadth and provide durable protection from SARS-CoV-2
npj Vaccines 2024cited by 26position: middledoi
SARS-CoV-2 evolution in the Omicron era
Nature Microbiology 2023cited by 133position: middledoi
Sensitivity of the SARS-CoV-2 BA.2.86 variant to prevailing neutralising antibody responses
The Lancet Infectious Diseases 2023cited by 85position: firstdoi
Vaccine-induced correlate of protection against fatal COVID-19 in older and frail adults during waves of neutralization-resistant variants of concern: an observational study
The Lancet Regional Health - Europe 2023cited by 28position: middledoi
Vaccination of SARS-CoV-2-infected individuals expands a broad range of clonally diverse affinity-matured B cell lineages
Nature Communications 2023cited by 20position: middledoi
Frequent use of IGHV3-30-3 in SARS-CoV-2 neutralizing antibody responses
Frontiers in Virology 2023cited by 13position: middledoi
Omicron sublineage BA.2.75.2 exhibits extensive escape from neutralising antibodies
The Lancet Infectious Diseases 2022cited by 106position: firstdoi
Neutralisation sensitivity of the SARS-CoV-2 omicron (B.1.1.529) variant: a cross-sectional study
The Lancet Infectious Diseases 2022cited by 93position: firstdoi
A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo
Nature Communications 2022cited by 86position: middledoi
Evasion of neutralising antibodies by omicron sublineage BA.2.75
The Lancet Infectious Diseases 2022cited by 86position: firstdoi
Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies
Immunity 2022cited by 49position: middledoi
Multivariate mining of an alpaca immune repertoire identifies potent cross-neutralizing SARS-CoV-2 nanobodies
Science Advances 2022cited by 41position: middledoi
Longitudinal single-cell analysis of SARS-CoV-2–reactive B cells uncovers persistence of early-formed, antigen-specific clones
JCI Insight 2022cited by 26position: middledoi
SARS-CoV-2 protein subunit vaccination of mice and rhesus macaques elicits potent and durable neutralizing antibody responses
Cell Reports Medicine 2021cited by 51position: middledoi
Adjuvanted SARS-CoV-2 spike protein elicits neutralizing antibodies and CD4 T cell responses after a single immunization in mice
EBioMedicine 2021cited by 47position: middledoi
An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction
Nature Communications 2020cited by 359position: middledoi
Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2
Nature Communications 2020cited by 163position: middledoi
Integrin α <sub>4</sub> β <sub>7</sub> expression on peripheral blood CD4 <sup>+</sup> T cells predicts HIV acquisition and disease progression outcomes
Science Translational Medicine 2018cited by 97position: middledoi
Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
Nature 2014cited by 749position: middledoi
FUBAR: A Fast, Unconstrained Bayesian AppRoximation for Inferring Selection
Molecular Biology and Evolution 2013cited by 1,436position: middledoi
Evolution of an HIV glycan–dependent broadly neutralizing antibody epitope through immune escape
Nature Medicine 2012cited by 295position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Ben Murrell · Karolinska Institutet19 papers (2013–2024)Gunilla B. Karlsson Hedestam · Science for Life Laboratory11 papers (2020–2024)Leo Hanke · Karolinska Institutet8 papers (2020–2024)Chang-Il Kim · Korean Academy of Science and Technology8 papers (2021–2024)Gerald M. McInerney · Karolinska Institutet8 papers (2020–2024)Xaquín Castro Dopico · Aarhus University5 papers (2021–2024)Jan Albert · Karolinska University Hospital5 papers (2022–2024)B.M. Hallberg · Institute for Biomedicine5 papers (2020–2024)Hrishikesh Das · Karolinska Institutet5 papers (2020–2024)Laura Perez Vidakovics · Karolinska Institutet5 papers (2020–2022)Martin Corcoran · Karolinska Institutet5 papers (2020–2024)Thomas P. Peacock · The Pirbright Institute5 papers (2022–2024)Pradeepa Pushparaj · Karolinska Institutet4 papers (2021–2024)Sandra Muschiol · Karolinska University Hospital3 papers (2022–2023)Kenta Sato · Karolinska Institutet3 papers (2022–2023)Alec Pankow · University of Washington3 papers (2022–2022)Sai T. Reddy · ETH Zurich3 papers (2022–2022)Julian Fischbach · Karolinska Institutet3 papers (2022–2022)Jonathan M. Coquet · University of Copenhagen3 papers (2021–2022)Simon Ekström · Lund University3 papers (2022–2023)