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Brent R. Stockwell

Columbia University Irving Medical Center · US
Area of research
Pulmonary and Respiratory Medicine · Molecular Biology
Research interest
Research interests include Ferroptosis and cancer prognosis, RNA modifications and cancer, Cancer, Lipids, and Metabolism, and Computational Drug Discovery Methods.
h-index
103
citations
123,808
works
325
NIH funding
primary concept
Biology
email

Recent publications

Hepatic stellate cells control liver zonation, size and functions via R-spondin 3
Nature 2025cited by 73position: middledoi
GPX4 regulates lipid peroxidation and ferroptosis of stored red blood cells
Blood Red Cells & Iron 2025cited by 7position: middledoi
Ferroptosis in health and disease
Redox Biology 2024cited by 283position: middledoi
A guideline on the molecular ecosystem regulating ferroptosis
Nature Cell Biology 2024cited by 238position: middledoi
Ferroptosis regulates hemolysis in stored murine and human red blood cells
Blood 2024cited by 40position: middledoi
A cell state-specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma
The EMBO Journal 2024cited by 20position: middledoi
Secreted Apoe rewires melanoma cell state vulnerability to ferroptosis
Science Advances 2024cited by 17position: middledoi
NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8
Science Advances 2023cited by 454position: middledoi
Identification of essential sites of lipid peroxidation in ferroptosis
Nature Chemical Biology 2023cited by 387position: lastdoi
Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP)
Nature Cell Biology 2023cited by 168position: middledoi
Organ Mapping Antibody Panels: a community resource for standardized multiplexed tissue imaging
Nature Methods 2023cited by 44position: middledoi
Discovery of Anticancer Agents of Diverse Natural Origin
Journal of Natural Products 2022cited by 50position: middledoi
Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations
Cancer Cell 2021cited by 399position: middledoi
An expanded universe of cancer targets
Cell 2021cited by 219position: middledoi
Characterization of a patient-derived variant of GPX4 for precision therapy
Nature Chemical Biology 2021cited by 95position: lastdoi
Cysteine depletion induces pancreatic tumor ferroptosis in mice
Science 2020cited by 1,233position: middledoi
Energy-stress-mediated AMPK activation inhibits ferroptosis
Nature Cell Biology 2020cited by 1,101position: middledoi
Intercellular interaction dictates cancer cell ferroptosis via NF2–YAP signalling
Nature 2019cited by 1,100position: middledoi
Publisher Correction: Intercellular interaction dictates cancer cell ferroptosis via NF2–YAP signalling
Nature 2019cited by 36position: middledoi
Leveraging insights into cancer metabolism—a symposium report
Annals of the New York Academy of Sciences 2019cited by 4position: middledoi
FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation
Nature Chemical Biology 2018cited by 706position: lastdoi
Copper-Binding Small Molecule Induces Oxidative Stress and Cell-Cycle Arrest in Glioblastoma-Patient-Derived Cells
Cell chemical biology 2018cited by 108position: lastdoi
A Stem Cell-Based Screening Platform Identifies Compounds that Desensitize Motor Neurons to Endoplasmic Reticulum Stress
Molecular Therapy 2018cited by 53position: middledoi
Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease
Cell 2017cited by 7,317position: firstdoi
Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
Nature 2017cited by 1,976position: middledoi
Inhibition of neuronal ferroptosis protects hemorrhagic brain
JCI Insight 2017cited by 700position: middledoi
Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis
Nature Chemical Biology 2016cited by 2,772position: middledoi
Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis
Proceedings of the National Academy of Sciences 2016cited by 2,248position: lastdoi
Regulated necrosis: disease relevance and therapeutic opportunities
Nature Reviews Drug Discovery 2016cited by 615position: lastdoi
Cell-Line Selectivity Improves the Predictive Power of Pharmacogenomic Analyses and Helps Identify NADPH as Biomarker for Ferroptosis Sensitivity
Cell chemical biology 2016cited by 295position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Wan Seok Yang · Guangzhou Women and Children Medical Center8 papers (2012–2016)Rachid Skouta · Columbia University6 papers (2012–2014)Scott J. Dixon · Stanford University4 papers (2012–2015)Anna Kaplan · Education Authority4 papers (2012–2015)Miki Hayano · Columbia University4 papers (2012–2016)Eduard Reznik · Columbia University4 papers (2015–2023) · 4 papers (2016–2023)Nen C. Pagano · Columbia University3 papers (2015–2018)Matthew Welsch · Columbia University3 papers (2014–2014)Michael M. Gaschler · Columbia University3 papers (2015–2018)Andras J. Bauer · Boehringer Ingelheim (United States)3 papers (2012–2014)Donald C. Lo · Center for Translational Molecular Medicine3 papers (2014–2018)Reka R. Letso · Acorda Therapeutics (United States)2 papers (2013–2013)Christopher E. Henderson · Columbia University2 papers (2016–2018) · 2 papers (2016–2022)Marcus Conrad · Max Planck Institute of Biophysics2 papers (2016–2021)Eric D. Lee · Columbia University2 papers (2014–2015)Grier P. Page · Brown University2 papers (2024–2025)Caroline E. Gleason · Memorial Sloan Kettering Cancer Center2 papers (2012–2014)Denise Dunn · Duke University2 papers (2014–2015)