Area of research
Genetics · Psychiatry and Mental health
Research interest
Research interests include Genetic Associations and Epidemiology, Bipolar Disorder and Treatment, Genomic variations and chromosomal abnormalities, and Genetics and Neurodevelopmental Disorders.
Exploring penetrance of clinically relevant variants in over 800,000 humans from the Genome Aggregation Database
New Genomics Discoveries Across the Bipolar Disorder Spectrum Implicate Neurobiological and Developmental Pathways
Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions
Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia
A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts
The Genetic Architecture of Depression in Individuals of East Asian Ancestry
Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders
Identifying the Common Genetic Basis of Antidepressant Response
Characterisation of age and polarity at onset in bipolar disorder
Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank
A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank
Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns
Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression
Low-frequency variation in TP53 has large effects on head circumference and intracranial volume
International Consortium on the Genetics of Electroconvulsive Therapy and Severe Depressive Disorders (Gen-ECT-ic)
Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Contribution of Rare Copy Number Variants to Bipolar Disorder Risk Is Limited to Schizoaffective Cases
Age at first birth in women is genetically associated with increased risk of schizophrenia
Contribution of rare copy number variants to bipolar disorder risk is limited to schizoaffective cases
A National Population-Based E-cohort of People with Psychosis (PsyCymru) Linkage of Phenotypical and Genetic Data to Routinely Collected Records
Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder
Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia
Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium
Genetic effects influencing risk for major depressive disorder in China and Europe
Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes
Interaction between the <i>FTO</i> gene, body mass index and depression: meta-analysis of 13701 individuals
Genome‐wide significant locus for Research Diagnostic Criteria Schizoaffective Disorder Bipolar type
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders