Area of research
Molecular Biology · Immunology
Research interest
Research interests include Epigenetics and DNA Methylation, RNA modifications and cancer, Immune Cell Function and Interaction, and Acute Myeloid Leukemia Research.
Predicting gene expression state and prioritizing putative enhancers using 5hmC signal
Spatiotemporal resolution of germinal center Tfh cell differentiation and divergence from central memory CD4+ T cell fate
BATF and IRF4 cooperate to counter exhaustion in tumor-infiltrating CAR T cells
TET deficiency perturbs mature B cell homeostasis and promotes oncogenesis associated with accumulation of G-quadruplex and R-loop structures
Roles of TET and TDG in DNA demethylation in proliferating and non-proliferating immune cells
Whole-genome analysis of TET dioxygenase function in regulatory T cells
TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8 <sup>+</sup> T cell exhaustion
TET enzymes augment activation-induced deaminase (AID) expression via 5-hydroxymethylcytosine modifications at the <i>Aicda</i> superenhancer
Targeting the NFAT:AP-1 transcriptional complex on DNA with a small-molecule inhibitor
Tet2 and Tet3 cooperate with B-lineage transcription factors to regulate DNA modification and chromatin accessibility
TET proteins regulate the lineage specification and TCR-mediated expansion of iNKT cells
Acute loss of TET function results in aggressive myeloid cancer in mice