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Jacqueline T. Hecht

University of California System · US
Area of research
Genetics · Rheumatology
Research interest
Research interests include Biology, Genetics, Genome-wide association study, Craniofacial, Single-nucleotide polymorphism, and Medicine.
h-index
citations
2,097
works
29
NIH funding
primary concept
email

Recent publications

Sustained growth-promoting effects of vosoritide in children with achondroplasia from an ongoing phase 3 extension study
Med 2024cited by 16position: middledoi
Trio-based GWAS identifies novel associations and subtype-specific risk factors for cleft palate
Human Genetics and Genomics Advances 2023cited by 14position: middledoi
Lifetime impact of achondroplasia: Current evidence and perspectives on the natural history
Bone 2021cited by 107position: middledoi
Genome-Wide Association Study of Non-syndromic Orofacial Clefts in a Multiethnic Sample of Families and Controls Identifies Novel Regions
Frontiers in Cell and Developmental Biology 2021cited by 33position: middledoi
DNA Methylation Variation Is Identified in Monozygotic Twins Discordant for Non-syndromic Cleft Lip and Palate
Frontiers in Cell and Developmental Biology 2021cited by 24position: middledoi
Genome-wide Enrichment of De Novo Coding Mutations in Orofacial Cleft Trios
The American Journal of Human Genetics 2020cited by 96position: middledoi
A systematic genetic analysis and visualization of phenotypic heterogeneity among orofacial cleft GWAS signals
Genetic Epidemiology 2019cited by 50position: middledoi
Whole genome sequencing of orofacial cleft trios from the Gabriella Miller Kids First Pediatric Research Consortium identifies a new locus on chromosome 21
Human Genetics 2019cited by 48position: middledoi
<i>PBX‐WNT‐P63‐IRF6</i>pathway in nonsyndromic cleft lip and palate
Birth Defects Research 2019cited by 27position: lastdoi
Genome‐wide interaction studies identify sex‐specific risk alleles for nonsyndromic orofacial clefts
Genetic Epidemiology 2018cited by 25position: middledoi
Knockdown of Crispld2 in zebrafish identifies a novel network for nonsyndromic cleft lip with or without cleft palate candidate genes
European Journal of Human Genetics 2018cited by 16position: lastdoi
Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate
Human Genetics 2017cited by 184position: middledoi
Multiethnic GWAS Reveals Polygenic Architecture of Earlobe Attachment
The American Journal of Human Genetics 2017cited by 46position: middledoi
Role of <i><scp>WNT</scp>10A</i> in failure of tooth development in humans and zebrafish
Molecular Genetics & Genomic Medicine 2017cited by 32position: middledoi
Identification of 16q21 as a modifier of nonsyndromic orofacial cleft phenotypes
Genetic Epidemiology 2017cited by 26position: middledoi
A multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24.2, 17q23 and 19q13
Human Molecular Genetics 2016cited by 229position: middledoi
Genome-Wide Association Study Reveals Multiple Loci Influencing Normal Human Facial Morphology
PLoS Genetics 2016cited by 179position: middledoi
A Genome-wide Association Study of Nonsyndromic Cleft Palate Identifies an Etiologic Missense Variant in GRHL3
The American Journal of Human Genetics 2016cited by 177position: middledoi
Functional Assessment of Clubfoot Associated HOXA9, TPM1, and TPM2 Variants Suggests a Potential Gene Regulation Mechanism
Clinical Orthopaedics and Related Research 2016cited by 36position: lastdoi
Identification of Functional Variants for Cleft Lip with or without Cleft Palate in or near PAX7, FGFR2, and NOG by Targeted Sequencing of GWAS Loci
The American Journal of Human Genetics 2015cited by 173position: middledoi
The 3D Facial Norms Database: Part 1. A Web-Based Craniofacial Anthropometric and Image Repository for the Clinical and Research Community
The Cleft Palate-Craniofacial Journal 2015cited by 110position: middledoi
Regulatory variant in<i><scp>FZD</scp>6</i>gene contributes to nonsyndromic cleft lip and palate in an African‐American family
Molecular Genetics & Genomic Medicine 2015cited by 27position: lastdoi
Mutations in PIEZO2 Cause Gordon Syndrome, Marden-Walker Syndrome, and Distal Arthrogryposis Type 5
The American Journal of Human Genetics 2014cited by 217position: middledoi
Further evidence suggesting a role for variation in <i>ARHGAP29</i> variants in nonsyndromic cleft lip/palate
Birth Defects Research Part A Clinical and Molecular Teratology 2014cited by 32position: lastdoi
Genome-wide association study identifies new disease loci for isolated clubfoot
Journal of Medical Genetics 2014cited by 28position: middledoi
Studies of <i>TBX4</i> and chromosome 17q23.1q23.2: An uncommon cause of nonsyndromic clubfoot
American Journal of Medical Genetics Part A 2012cited by 44position: lastdoi
Association of <i>MMP3</i> and <i>TIMP2</i> promoter polymorphisms with nonsyndromic oral clefts
Birth Defects Research Part A Clinical and Molecular Teratology 2012cited by 36position: middledoi
Association of <i>AXIN2</i> with Non-syndromic Oral Clefts in Multiple Populations
Journal of Dental Research 2012cited by 33position: middledoi
Craniofacial abnormalities result from knock down of nonsyndromic clefting gene, <i>crispld2</i>, in zebrafish
genesis 2012cited by 32position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Susan H. Blanton · University of Miami10 papers (2012–2021)Mary L. Marazita · University of North Carolina at Chapel Hill10 papers (2012–2023)Jeffrey C. Murray · University of Iowa9 papers (2015–2023) · 9 papers (2015–2023)Elizabeth J. Leslie · Emory University8 papers (2016–2023)Azeez Butali · University of Iowa7 papers (2017–2023)Eleanor Feingold · Oregon State University7 papers (2016–2021)Ariadne Letra · University of Houston7 papers (2012–2019)Alexandre R. Vieira · Institut national de recherche en sciences et technologies du numérique7 papers (2012–2021)Iêda M. Orioli · Michigan State University6 papers (2012–2021) · 6 papers (2017–2023)John R. Shaffer · University of Pittsburgh5 papers (2016–2021)Lina M. Moreno · University of Iowa5 papers (2015–2019)Lorena Maili · University of Houston5 papers (2014–2019) · 5 papers (2017–2021)Terri H. Beaty · Johns Hopkins University5 papers (2017–2023)Eric C. Swindell · The University of Texas at Austin4 papers (2012–2018)John B. Mulliken · Boston University4 papers (2014–2019)Qiuping Yuan · The University of Texas Health Science Center at Houston4 papers (2012–2018) · 4 papers (2012–2018)