Area of research
Oncology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Cancer Cells and Metastasis, Lung Cancer Treatments and Mutations, Advanced Breast Cancer Therapies, and Cancer-related Molecular Pathways.
Selective CDK7 Inhibition Suppresses Cell Cycle Progression and MYC Signaling While Enhancing Apoptosis in Therapy-resistant Estrogen Receptor–positive Breast Cancer
Mitochondrial reprogramming by activating OXPHOS via glutamine metabolism in African American patients with bladder cancer
The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cells
Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy
Regorafenib is effective against neuroblastoma in vitro and in vivo and inhibits the RAS/MAPK, PI3K/Akt/mTOR and Fos/Jun pathways
Metformin and an insulin/IGF-1 receptor inhibitor are synergistic in blocking growth of triple-negative breast cancer
The Progestin Receptor Interactome in the Female Mouse Hypothalamus: Interactions with Synaptic Proteins Are Isoform Specific and Ligand Dependent
Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation
FOXA1 overexpression mediates endocrine resistance by altering the ER transcriptome and IL-8 expression in ER-positive breast cancer
Generation of an in vitro 3D PDAC stroma rich spheroid model
Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer
The REGγ-proteasome forms a regulatory circuit with IκBɛ and NFκB in experimental colitis