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Erin L. Heinzen

University of North Carolina at Chapel Hill · US
Area of research
Genetics · Psychiatry and Mental health
Research interest
Research interests include Genomics and Rare Diseases, Epilepsy research and treatment, Genetics and Neurodevelopmental Disorders, and Genomic variations and chromosomal abnormalities.
h-index
54
citations
16,338
works
151
NIH funding
primary concept
email

Recent publications

Contribution of Somatic Ras/Raf/Mitogen-Activated Protein Kinase Variants in the Hippocampus in Drug-Resistant Mesial Temporal Lobe Epilepsy
JAMA Neurology 2023cited by 72position: middledoi
Genome-wide identification and phenotypic characterization of seizure-associated copy number variations in 741,075 individuals
Nature Communications 2023cited by 54position: middledoi
Exome sequencing of ATP1A3-negative cases of alternating hemiplegia of childhood reveals SCN2A as a novel causative gene
European Journal of Human Genetics 2023cited by 7position: lastdoi
Common risk variants for epilepsy are enriched in families previously targeted for rare monogenic variant discovery
EBioMedicine 2022cited by 40position: middledoi
<i>CSNK2B</i>: A broad spectrum of neurodevelopmental disability and epilepsy severity
Epilepsia 2021cited by 32position: middledoi
De novo TRIM8 variants impair its protein localization to nuclear bodies and cause developmental delay, epilepsy, and focal segmental glomerulosclerosis
The American Journal of Human Genetics 2021cited by 26position: middledoi
The benefit of diagnostic whole genome sequencing in schizophrenia and other psychotic disorders
Molecular Psychiatry 2021cited by 25position: middledoi
Epilepsy subtype-specific copy number burden observed in a genome-wide study of 17 458 subjects
Brain 2020cited by 80position: middledoi
Development and validation of a predictive model of drug-resistant genetic generalized epilepsy
Neurology 2020cited by 31position: middledoi
Expansion of the GRIA2 phenotypic representation: a novel de novo loss of function mutation in a case with childhood onset schizophrenia
Journal of Human Genetics 2020cited by 27position: middledoi
Autism and developmental disability caused by <i>KCNQ3</i> gain‐of‐function variants
Annals of Neurology 2019cited by 116position: middledoi
Missense Variants in the Histone Acetyltransferase Complex Component Gene TRRAP Cause Autism and Syndromic Intellectual Disability
The American Journal of Human Genetics 2019cited by 54position: middledoi
Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies
Nature Communications 2018cited by 506position: middledoi
The copy number variation landscape of congenital anomalies of the kidney and urinary tract
Nature Genetics 2018cited by 239position: middledoi
Somatic <i>SLC35A2</i> variants in the brain are associated with intractable neocortical epilepsy
Annals of Neurology 2018cited by 134position: lastdoi
De novo and inherited private variants in MAP1B in periventricular nodular heterotopia
PLoS Genetics 2018cited by 74position: firstdoi
Refining the phenotype associated with <i>GNB1</i> mutations: Clinical data on 18 newly identified patients and review of the literature
American Journal of Medical Genetics Part A 2018cited by 62position: middledoi
<i>NBEA</i>: Developmental disease gene with early generalized epilepsy phenotypes
Annals of Neurology 2018cited by 54position: middledoi
De Novo Mutations in PPP3CA Cause Severe Neurodevelopmental Disease with Seizures
The American Journal of Human Genetics 2017cited by 69position: lastdoi
Germline De Novo Mutations in GNB1 Cause Severe Neurodevelopmental Disability, Hypotonia, and Seizures
The American Journal of Human Genetics 2016cited by 119position: middledoi
Clinical profile of patients with ATP1A3 mutations in Alternating Hemiplegia of Childhood—a study of 155 patients
Orphanet Journal of Rare Diseases 2015cited by 154position: middledoi
Time from convulsive status epilepticus onset to anticonvulsant administration in children
Neurology 2015cited by 125position: middledoi
Genic Intolerance to Functional Variation and the Interpretation of Personal Genomes
PLoS Genetics 2013cited by 991position: middledoi
<i>SLC25A22</i>is a novel gene for migrating partial seizures in infancy
Annals of Neurology 2013cited by 116position: middledoi
Gaps and opportunities in refractory status epilepticus research in children: A multi-center approach by the Pediatric Status Epilepticus Research Group (pSERG)
Seizure 2013cited by 106position: middledoi
Somatic Activation of AKT3 Causes Hemispheric Developmental Brain Malformations
Neuron 2012cited by 477position: middledoi
De novo mutations in ATP1A3 cause alternating hemiplegia of childhood
Nature Genetics 2012cited by 421position: firstdoi
Exome Sequencing and Functional Validation in Zebrafish Identify GTDC2 Mutations as a Cause of Walker-Warburg Syndrome
The American Journal of Human Genetics 2012cited by 184position: middledoi
Exome Sequencing Followed by Large-Scale Genotyping Suggests a Limited Role for Moderately Rare Risk Factors of Strong Effect in Schizophrenia
The American Journal of Human Genetics 2012cited by 91position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

David B. Goldstein · Structural Genomics Consortium4 papers (2012–2021)Brenda J. Barry · Boston Children's Hospital3 papers (2012–2013)Christopher A. Walsh · Boston Children's Hospital3 papers (2012–2013)Annapurna Poduri · Broad Institute3 papers (2012–2018)Jennifer N. Partlow · Boston Children's Hospital2 papers (2012–2013)Mohamad A. Mikati · Duke University2 papers (2013–2023)Ingrid E. Scheffer · Neurosciences Institute2 papers (2013–2022)Melanie Bahlo · The University of Western Australia2 papers (2018–2022)Vimla S. Aggarwal · Columbia University2 papers (2020–2021)Lior Greenbaum · Hebrew University of Jerusalem2 papers (2020–2021)Daniel Hughes · Oxford University Hospitals NHS Trust2 papers (2020–2021)David B. Goldstein · NewYork–Presbyterian Hospital2 papers (2013–2020)Anna Alkelai · Columbia University2 papers (2020–2021)R. Sean Hill · Auckland City Hospital2 papers (2012–2012)James J. Riviello · Texas Children's Hospital2 papers (2012–2013)Princess C. Elhosary · Broad Institute2 papers (2012–2013)Mustafa A. Salih · Heart Hospital Baylor Plano2 papers (2012–2013)A. James Barkovich · University of California, San Francisco2 papers (2012–2013)Andrew S. Allen · Duke University2 papers (2013–2018) · 2 papers (2012–2012)