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Nikolaj Frost

Humboldt-Universität zu Berlin · DE
Area of research
Pulmonary and Respiratory Medicine · Oncology
Research interest
Research interests include Lung Cancer Treatments and Mutations, Lung Cancer Diagnosis and Treatment, Cancer Immunotherapy and Biomarkers, and Lung Cancer Research Studies.
h-index
24
citations
1,814
works
133
NIH funding
primary concept
email

Recent publications

Treatment of NSCLC after chemoimmunotherapy — are we making headway?
Nature Reviews Clinical Oncology 2025cited by 19position: middledoi
Practice Variation in Perioperative Dexamethasone Use and Outcomes in Brain Metastasis Resection
JAMA Network Open 2025cited by 10position: middledoi
AI-powered spatial cell phenomics enhances risk stratification in non-small cell lung cancer
Nature Communications 2025cited by 8position: middledoi
Re-resection of brain metastases – outcomes of an institutional cohort study and literature review
BMC Cancer 2025cited by 5position: middledoi
Clinical characteristics and outcomes in leptomeningeal disease with or without brain metastasis: insights from an explorative data analysis of the Charité LMD registry
Journal of Neuro-Oncology 2025cited by 4position: middledoi
First-line nivolumab plus ipilimumab in pleural mesothelioma: Efficacy and safety data from the real-world MesoNet study
Lung Cancer 2025cited by 3position: middledoi
Recruiting patients into a healthcare services trial: lessons learned from a feasibility study to investigate a patient-oriented navigation intervention for age-associated diseases
BMC Health Services Research 2025cited by 1position: middledoi
RMTD-05 PERI-OPERATIVE DEXAMETHASONE USE IN BRAIN METASTASIS SURGERY: ANALYSIS OF PRACTICE VARIATION ACROSS EIGHT NEUROSURGICAL CENTERS
Neuro-Oncology Advances 2025cited by 0position: middledoi
1879P Retrospective multicenter analysis of real-world clinical data in patients with PD-L1-negative stage IV non-small cell lung cancer in Germany: “REMARCS-PD-L1-neG
Annals of Oncology 2025cited by 0position: middledoi
Sotorasib in KRAS G12C-mutated non-small cell lung cancer: A multicenter real-world experience from the compassionate use program in Germany
European Journal of Cancer 2024cited by 40position: middledoi
Clinical outcomes with perioperative nivolumab (NIVO) by nodal status among patients (pts) with stage III resectable NSCLC: Results from the phase 3 CheckMate 77T study.
Journal of Clinical Oncology 2024cited by 21position: middledoi
Non–Small Cell Lung Cancer Metastatic Without Oncogenic Alterations
American Society of Clinical Oncology Educational Book 2024cited by 20position: firstdoi
First-line immunotherapy for lung cancer with MET exon 14 skipping and the relevance of TP53 mutations
European Journal of Cancer 2024cited by 19position: middledoi
TTF-1 is a highly sensitive but not fully specific marker for pulmonary and thyroidal cancer: a tissue microarray study evaluating more than 17,000 tumors from 152 different tumor entities
Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin 2024cited by 13position: middledoi
117O Stereotactic body radiotherapy (SBRT) with pembrolizumab (pembro) for unresected stage I/II non-small cell lung cancer (NSCLC): The randomized, double-blind, phase III KEYNOTE-867 study
Immuno-Oncology Technology 2024cited by 10position: middledoi
Predictive role of intracranial PD-L1 expression in a real-world cohort of NSCLC patients treated with immune checkpoint inhibition following brain metastasis resection
Journal of Neuro-Oncology 2024cited by 5position: middledoi
Four-year outcomes and circulating tumor DNA (ctDNA) analysis of pembrolizumab (pembro) plus concurrent chemoradiation therapy (cCRT) in unresectable, locally advanced, stage III non–small-cell lung cancer (NSCLC): From KEYNOTE-799.
Journal of Clinical Oncology 2024cited by 5position: middledoi
TTF-1 negativity in synchronous M1b/M1c wildtype lung adenocarcinoma brain metastases predicts worse survival with increased risk of intracranial progression
Journal of Neuro-Oncology 2024cited by 4position: lastdoi
Prognostic Value of Thyroid Transcription Factor 1 Expression in Newly Diagnosed, Treatment-Naïve Non-Small-Cell Lung Cancer Adenocarcinoma Brain Metastasis
Brain and Spine 2024cited by 0position: middledoi
Outcome of First-Line Treatment With Pembrolizumab According to KRAS/TP53 Mutational Status for Nonsquamous Programmed Death-Ligand 1–High (≥50%) NSCLC in the German National Network Genomic Medicine Lung Cancer
Journal of Thoracic Oncology 2023cited by 46position: middledoi
Immune signatures of checkpoint inhibitor-induced autoimmunity—A focus on neurotoxicity
Neuro-Oncology 2023cited by 24position: middledoi
A machine learning tool to improve prediction of mediastinal lymph node metastases in non-small cell lung cancer using routinely obtainable [18F]FDG-PET/CT parameters
European Journal of Nuclear Medicine and Molecular Imaging 2023cited by 24position: middledoi
Management, risk factors and prognostic impact of checkpoint-inhibitor pneumonitis (CIP) in lung cancer – A multicenter observational analysis
Lung Cancer 2023cited by 16position: firstdoi
Feasibility of a patient-oriented navigation programme for patients with lung cancer or stroke in Germany: Protocol of the CoreNAVI study
PLoS ONE 2023cited by 11position: middledoi
TTF-1 status in early-stage lung adenocarcinoma is an independent predictor of relapse and survival superior to tumor grading
European Journal of Cancer 2023cited by 8position: lastdoi
Rationale and Design of the Phase II ANTELOPE Study of Atezolizumab, Carboplatin and nab-Paclitaxel vs. Pembrolizumab, Platinum and Pemetrexed in TTF-1 Negative, Metastatic Lung Adenocarcinoma (AIO-TRK-0122)
Clinical Lung Cancer 2023cited by 5position: firstdoi
1405P Sotorasib in KRAS G12C-mutated NSCLC: A multicenter real-world experience from the expanded access program in Germany
Annals of Oncology 2023cited by 2position: middledoi
Clinical predictors of survival in patients with relapsed/refractory small-cell lung cancer treated with checkpoint inhibitors: a German multicentric real-world analysis
Therapeutic Advances in Medical Oncology 2022cited by 27position: middledoi
The impact of TP53 co-mutations and immunologic microenvironment on outcome of lung cancer with EGFR exon 20 insertions
European Journal of Cancer 2022cited by 25position: middledoi
Effectiveness of Immune Checkpoint Inhibition vs Chemotherapy in Combination With Radiation Therapy Among Patients With Non–Small Cell Lung Cancer and Brain Metastasis Undergoing Neurosurgical Resection
JAMA Network Open 2022cited by 24position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Christian Grohé · Saarland University11 papers (2018–2025)Matthias Raspe · Charité - Universitätsmedizin Berlin10 papers (2018–2024)Maximilian von Laffert · University Hospital Leipzig8 papers (2018–2021)Frank Griesinger · Technische Universität Dresden8 papers (2021–2025)Sebastian Ochsenreither · Deutschen Konsortium für Translationale Krebsforschung7 papers (2018–2023)Norbert Suttorp · German Center for Lung Research7 papers (2018–2022)Martin Witzenrath · German Centre for Cardiovascular Research7 papers (2018–2023)Martin Reck · Iomedico (Germany)6 papers (2021–2025)David Horst · German Cancer Research Center6 papers (2019–2024)Julia Onken · German Society of Surgery6 papers (2022–2025)Petros Christopoulos · Torbay Hospital6 papers (2021–2025)Bettina Temmesfeld‐Wollbrück · Berlin Institute of Health at Charité - Universitätsmedizin Berlin5 papers (2018–2021)David Capper · German Cancer Research Center5 papers (2019–2025)Jens Neudecker · Humboldt-Universität zu Berlin5 papers (2018–2023)David Wasilewski · German Cancer Research Center5 papers (2022–2025)Jens C. Rückert · Charité - Universitätsmedizin Berlin5 papers (2018–2023)Peter Vajkoczy · Humboldt-Universität zu Berlin5 papers (2022–2025)Dirk Böhmer · Humboldt-Universität zu Berlin5 papers (2018–2023) · 4 papers (2021–2023)Frederick Klauschen · Institute of Clinical Cancer Research4 papers (2019–2023)