Area of research
Oncology · Cancer Research
Research interest
Research interests include Colorectal cancer, Cancer research, Medicine, Cancer, KRAS, and Biology.
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer
<i>RAS/RAF</i> Comutation and <i>ERBB2</i> Copy Number Modulates HER2 Heterogeneity and Responsiveness to HER2-directed Therapy in Colorectal Cancer
Effective drug combinations in breast, colon and pancreatic cancer cells
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
Quantifying single-cell ERK dynamics in colorectal cancer organoids reveals EGFR as an amplifier of oncogenic MAPK pathway signalling
Molecular Subtyping Combined with Biological Pathway Analyses to Study Regorafenib Response in Clinically Relevant Mouse Models of Colorectal Cancer
EGFR Blockade Reverts Resistance to KRASG12C Inhibition in Colorectal Cancer
Abstract 1685: The EurOPDX Research Infrastructure: Supporting European and worldwide cancer research with patient-derived xenografts
Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens
Adaptive mutability of colorectal cancers in response to targeted therapies
PO-049 EGFR blockade induces a paneth cell-like phenotype with rewired signalling dependencies in CRC tumoursat maximal response
Interrogating open issues in cancer precision medicine with patient-derived xenografts
Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer
PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models
The genomic landscape of response to EGFR blockade in colorectal cancer
NOTCH3 Signaling Regulates MUSASHI-1 Expression in Metastatic Colorectal Cancer Cells
MET dysregulation is a hallmark of aggressive disease in multiple myeloma patients