Area of research
Molecular Biology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Sphingolipid Metabolism and Signaling, Neonatal Respiratory Health Research, Fibroblast Growth Factor Research, and Epigenetics and DNA Methylation.
Sphingosine kinase 1 regulates lysyl oxidase through STAT3 in hyperoxia-mediated neonatal lung injury
Nuclear Sphingosine-1-phosphate Lyase Generated ∆2-hexadecenal is A Regulator of HDAC Activity and Chromatin Remodeling in Lung Epithelial Cells
Sphingosine Kinase 1/S1P Signaling Contributes to Pulmonary Fibrosis by Activating Hippo/YAP Pathway and Mitochondrial Reactive Oxygen Species in Lung Fibroblasts
S1P and plasmalogen derived fatty aldehydes in cellular signaling and functions
Neonatal therapy with PF543, a sphingosine kinase 1 inhibitor, ameliorates hyperoxia-induced airway remodeling in a murine model of bronchopulmonary dysplasia
Phospholipase D2 restores endothelial barrier function by promoting PTPN14-mediated VE-cadherin dephosphorylation
<i>Pseudomonas aeruginosa</i>stimulates nuclear sphingosine-1-phosphate generation and epigenetic regulation of lung inflammatory injury
Genetic deletion of Sphk2 confers protection against Pseudomonas aeruginosa mediated differential expression of genes related to virulent infection and inflammation in mouse lung
Nuclear lipid mediators: Role of nuclear sphingolipids and sphingosine‐1‐phosphate signaling in epigenetic regulation of inflammation and gene expression
Sphingolipids in Ventilator Induced Lung Injury: Role of Sphingosine-1-Phosphate Lyase
Expression profiling of genes regulated by sphingosine kinase1 signaling in a murine model of hyperoxia induced neonatal bronchopulmonary dysplasia
Targeting sphingosine-1-phosphate signaling in lung diseases
Epigenetic regulation of pro-inflammatory cytokine secretion by sphingosine 1-phosphate (S1P) in acute lung injury: Role of S1P lyase
Hyperoxia-induced p47<sup><i>phox</i></sup>activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P<sub>1&2</sub>signaling axis in lung endothelium
Role of Sphingosine Kinase 1 and S1P Transporter Spns2 in HGF-mediated Lamellipodia Formation in Lung Endothelium
Sphingosine-1-phosphate lyase is an endogenous suppressor of pulmonary fibrosis: role of S1P signalling and autophagy
Reduced <i>DOCK4</i> expression leads to erythroid dysplasia in myelodysplastic syndromes
Reactive oxygen species at the crossroads of inflammasome and inflammation
High Resolution Methylome Analysis Reveals Widespread Functional Hypomethylation during Adult Human Erythropoiesis
Coronin 1B Regulates S1P-Induced Human Lung Endothelial Cell Chemotaxis: Role of PLD2, Protein Kinase C and Rac1 Signal Transduction