Area of research
Molecular Biology · Nephrology
Research interest
Research interests include Internal medicine, Klotho, Endocrinology, Fibroblast growth factor, Fibroblast growth factor receptor, and Biology.
A G protein–coupled, IP3/protein kinase C pathway controlling the synthesis of phosphaturic hormone FGF23
α-Klotho is a non-enzymatic molecular scaffold for FGF23 hormone signalling
Inhibition of fibroblast growth factor 23 (FGF23) signaling rescues renal anemia
Fibroblast Growth Factor Binding Protein 3 (FGFBP3) impacts carbohydrate and lipid metabolism
Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer
FGF23 promotes renal calcium reabsorption through the TRPV5 channel
The demonstration of αKlotho deficiency in human chronic kidney disease with a novel synthetic antibody
Exploring mechanisms of FGF signalling through the lens of structural biology
Parathyroid-Specific Deletion of Klotho Unravels a Novel Calcineurin-Dependent FGF23 Signaling Pathway That Regulates PTH Secretion
Arterial Klotho Expression and FGF23 Effects on Vascular Calcification and Function
Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor γ
FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2–SGK1 signaling pathway
Conversion of a Paracrine Fibroblast Growth Factor into an Endocrine Fibroblast Growth Factor
The Alternatively Spliced Acid Box Region Plays a Key Role in FGF Receptor Autoinhibition
Klotho Coreceptors Inhibit Signaling by Paracrine Fibroblast Growth Factor 8 Subfamily Ligands
FGF23 regulates renal sodium handling and blood pressure