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Rajeev Prabhakar

University of Miami · US
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Area of research
Molecular Biology · Physiology
Research interest
Research interests include Alzheimer's disease research and treatments, Protein Structure and Dynamics, Metal-Catalyzed Oxygenation Mechanisms, and Computational Drug Discovery Methods.
h-index
36
citations
3,699
works
147
NIH funding
primary concept
email

Recent publications

Hydrolytic Degradation of Key Plastic Pollutant Model Systems by a Discrete Metal–Oxo Cluster: A Combined Theoretical and Experimental Study
The Journal of Physical Chemistry B 2025cited by 2position: lastdoi
Consequences of Heterogeneity of Organic Molecules in Water: Enhanced Photodimerization of Olefins
Langmuir 2025cited by 2position: middledoi
A Multipurpose Metallophore and Its Copper Complexes with Diverse Catalytic Antioxidant Properties to Deal with Metal and Oxidative Stress Disorders: A Combined Experimental, Theoretical, and <i>In Vitro</i> Study
Inorganic Chemistry 2024cited by 13position: middledoi
Tuneable redox-responsive albumin-hitchhiking drug delivery to tumours for cancer treatment
Journal of Materials Chemistry B 2024cited by 9position: middledoi
Distinct chemical factors in hydrolytic reactions catalyzed by metalloenzymes and metal complexes
Chemical Communications 2023cited by 19position: lastdoi
Elucidating the Roles of Distinct Chemical Factors in the Hydrolytic Activities of Hetero- and Homonuclear Synthetic Analogues of Binuclear Metalloenzymes
ACS Catalysis 2023cited by 12position: lastdoi
Deconvoluting binding sites in amyloid nanofibrils using time-resolved spectroscopy
2023cited by 8position: middledoi
Structure-activity relationship of carbon nitride dots in inhibiting Tau aggregation
Carbon 2022cited by 36position: middledoi
Peptide hydrogel with self-healing and redox-responsive properties
Nano Convergence 2022cited by 33position: middledoi
Promiscuous Catalytic Activity of a Binuclear<i>Metallohydrolase</i>: Peptide and Phosphoester Hydrolyses
Journal of Chemical Information and Modeling 2022cited by 12position: lastdoi
Dynamics of Anthracene Excimer Formation within a Water-Soluble Nanocavity at Room Temperature
Journal of the American Chemical Society 2021cited by 59position: middledoi
Degradation of a Main Plastic Pollutant Polyethylene Terephthalate by Two Distinct Proteases (Neprilysin and Cutinase-like Enzyme)
Journal of Chemical Information and Modeling 2021cited by 34position: lastdoi
Remediation of environmentally hazardous organophosphates by artificial metalloenzymes
Current Opinion in Green and Sustainable Chemistry 2021cited by 14position: lastdoi
Organic Host Encapsulation Effects on Nitrosobenzene Monomer–Dimer Distribution and C–NO Bond Rotation in an Aqueous Solution
ACS Organic & Inorganic Au 2021cited by 10position: middledoi
Heteromeric three-stranded coiled coils designed using a Pb(ii)(Cys)3 template mediated strategy
Nature Chemistry 2020cited by 48position: middledoi
A Potent Host Defense Peptide Triggers DNA Damage and Is Active against Multidrug-Resistant Gram-Negative Pathogens
ACS Infectious Diseases 2020cited by 29position: middledoi
Effect of Chemically Distinct Substrates on the Mechanism and Reactivity of a Highly Promiscuous Metallohydrolase
ACS Catalysis 2020cited by 27position: lastdoi
Mechanisms of peptide and phosphoester hydrolysis catalyzed by two promiscuous metalloenzymes (insulin degrading enzyme and glycerophosphodiesterase) and their synthetic analogues
Wiley Interdisciplinary Reviews Computational Molecular Science 2020cited by 25position: lastdoi
Molecular Dynamics Investigation into the Effect of Zinc(II) on the Structure and Membrane Interactions of the Antimicrobial Peptide Clavanin A
The Journal of Physical Chemistry B 2019cited by 36position: middledoi
Ultrafast <i>trans → cis</i> Photoisomerization Dynamics of Alkyl-Substituted Stilbenes in a Supramolecular Capsule
The Journal of Physical Chemistry A 2019cited by 23position: middledoi
Effects of the Metal Ion on the Mechanism of Phosphodiester Hydrolysis Catalyzed by Metal-Cyclen Complexes
Frontiers in Chemistry 2019cited by 22position: lastdoi
Ultrafast Solvation Dynamics Reveal that Octa Acid Capsule’s Interior Dryness Depends on the Guest
The Journal of Physical Chemistry A 2019cited by 19position: middledoi
Investigating coordination flexibility of glycerophosphodiesterase (GpdQ) through interactions with mono-, di-, and triphosphoester (NPP, BNPP, GPE, and paraoxon) substrates
Physical Chemistry Chemical Physics 2019cited by 18position: lastdoi
Investigating Polyoxometalate–Protein Interactions at Chemically Distinct Binding Sites
The Journal of Physical Chemistry B 2018cited by 36position: lastdoi
Hydrolysis of chemically distinct sites of human serum albumin by polyoxometalate: A hybrid QM/MM (ONIOM) study
Journal of Computational Chemistry 2018cited by 24position: lastdoi
Formation of Catalytically Active Binuclear Center of Glycerophosphodiesterase: A Molecular Dynamics Study
The Journal of Physical Chemistry B 2018cited by 14position: lastdoi
CD11b activation suppresses TLR-dependent inflammation and autoimmunity in systemic lupus erythematosus
Journal of Clinical Investigation 2017cited by 110position: middledoi
Photochemical Identification of Molecular Binding Sites on the Surface of Amyloid-β Fibrillar Aggregates
Chem 2017cited by 35position: middledoi
Effects of Ligand Environment in Zr(IV) Assisted Peptide Hydrolysis
Journal of Chemical Information and Modeling 2017cited by 19position: lastdoi
Structural and Mechanical Properties of Amyloid Beta Fibrils: A Combined Experimental and Theoretical Approach
The Journal of Physical Chemistry Letters 2016cited by 39position: lastdoi

Grants

CAS: Development of Bio-inspired Catalysts for Hydrolysis: Insights from Theoretical Studies
NSF2102563$449,5442021–2025PIRePORTER
Development of Bio-inspired Synthetic Metallohydrolases Based on Theoretical Insights
NSF1664926$415,0002017–2021PIRePORTER
Development of Bio-Inspired Synthetic Metallopeptidases: Insight from Theoretical Studies
NSF1152846$351,0002012–2016PIRePORTER

Frequent collaborators

Thomas J. Paul · University of Michigan13 papers (2015–2020)Gaurav Sharma · Austen Riggs Center13 papers (2016–2021)Vindi M. Jayasinghe‐Arachchige · University of North Texas12 papers (2018–2023)Leonardo F. Serafim · University of Miami9 papers (2020–2025)Mehmet Özbil · Gebze Technical University7 papers (2012–2016)Arghya Barman · Fujifilm (Japan)7 papers (2012–2016)Qiaoyu Hu · Hebei Medical University7 papers (2018–2023)Lukun Wang · University of Miami6 papers (2021–2025)Vaidhyanathan Ramamurthy · University of Miami5 papers (2019–2025)Parth Rathee · University of Miami4 papers (2021–2025)Alfredo M. Angeles‐Boza · University of Connecticut4 papers (2012–2020)Sreerag N. Moorkkannur · University of Miami3 papers (2023–2025)Tingting Zhang · Shandong University3 papers (2014–2017)Jiawen Yang · Xi'an University of Architecture and Technology3 papers (2021–2024)Zachary Hoffmann · Arizona State University3 papers (2016–2017)Ram Prasad Bora · University of Southern California3 papers (2012–2016)Gerhard Schenk · University of Queensland3 papers (2018–2023) · 3 papers (2013–2023)Tatjana N. Parac‐Vogt · KU Leuven3 papers (2018–2025)Kyle J. Korshavn · University of Michigan–Ann Arbor2 papers (2015–2016)
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