Area of research
Molecular Biology · Pathology and Forensic Medicine
Research interest
Research interests include Genomics and Chromatin Dynamics, Genetic factors in colorectal cancer, Cancer Genomics and Diagnostics, and RNA and protein synthesis mechanisms.
DNA-guided transcription factor interactions extend human gene regulatory code
DNA-guided transcription factor cooperativity shapes face and limb mesenchyme
DNA methylation patterns of transcription factor binding regions characterize their functional and evolutionary contexts
Author Correction: Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates
Hold out the genome: a roadmap to solving the cis-regulatory code
Pioneer factors — key regulators of chromatin and gene expression
Sequence determinants of human gene regulatory elements
DNA methylation patterns of transcription factor binding regions characterize their functional and evolutionary contexts
Genetic and Epigenetic Characteristics of Inflammatory Bowel Disease–Associated Colorectal Cancer
Systematic analysis of binding of transcription factors to noncoding variants
Human cell transformation by combined lineage conversion and oncogene expression
Structural insights into the interaction between transcription factors and the nucleosome
Promoter Hypermethylation Promotes the Binding of Transcription Factor NFATc1, Triggering Oncogenic Gene Activation in Pancreatic Cancer
Author Correction: CRISPR-assisted detection of RNA–protein interactions in living cells
A comprehensive library of human transcription factors for cell fate engineering
CRISPR-assisted detection of RNA–protein interactions in living cells
Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans
Gain-of-function CEBPE mutation causes noncanonical autoinflammatory inflammasomopathy
The transcription factor FLI1 promotes cancer progression by affecting cell cycle regulation
The Human Transcription Factors
CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response
The interaction landscape between transcription factors and the nucleosome
Promoter capture Hi-C-based identification of recurrent noncoding mutations in colorectal cancer
Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima
Impact of cytosine methylation on DNA binding specificities of human transcription factors
Structural perspective of cooperative transcription factor binding
Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates
Transcription factor family‐specific DNA shape readout revealed by quantitative specificity models
Damaging heterozygous mutations in NFKB1 lead to diverse immunologic phenotypes
CRISPR/Cas9 screening using unique molecular identifiers