Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include RNA modifications and cancer, Cancer-related gene regulation, Epigenetics and DNA Methylation, and Cancer-related molecular mechanisms research.
FTO degrader impairs ribosome biogenesis and protein translation in acute myeloid leukemia
ALKBH1 Drives Tumorigenesis and Drug Resistance via tRNA-decoding Reprogramming and Codon-biased Translation
METTL16 promotes liver cancer stem cell self-renewal via controlling ribosome biogenesis and mRNA translation
YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies
The roles and implications of RNA m6A modification in cancer
QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism
TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal
RNA m6A reader YTHDF2 facilitates precursor miR-126 maturation to promote acute myeloid leukemia progression
METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis
RNA <i>N<sup>6</sup></i>-methyladenosine reader YTHDC1 is essential for TGF-beta-mediated metastasis of triple negative breast cancer
R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis
Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion
Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally
Sulforaphane‑induced epigenetic regulation of Nrf2 expression by DNA methyltransferase in human Caco‑2 cells
R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling