Area of research
Immunology · Endocrinology
Research interest
Research interests include interferon and immune responses, Legionella and Acanthamoeba research, Viral Infections and Vectors, and Autophagy in Disease and Therapy.
CRISPR-repressed toxin–antitoxin provides herd immunity against anti-CRISPR elements
A variant-proof SARS-CoV-2 vaccine targeting HR1 domain in S2 subunit of spike protein
Functional and Structural Characteristics of HLA-B*13:01-Mediated Specific T Cells Reaction in Dapsone-Induced Drug Hypersensitivity
Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity
Biochemical and structural characterization of the BioZ enzyme engaged in bacterial biotin synthesis pathway
HER2 recruits AKT1 to disrupt STING signalling and suppress antiviral defence and antitumour immunity
The Nuclear Matrix Protein SAFA Surveils Viral RNA and Facilitates Immunity by Activating Antiviral Enhancers and Super-enhancers
From Mosquitos to Humans: Genetic Evolution of Zika Virus
The emerging roles of the DDX41 protein in immunity and diseases
Structural basis for DNA recognition by STAT6
Functional Self-Assembling Peptide Nanofiber Hydrogels Designed for Nerve Degeneration
Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage
Structure of the Leanyer orthobunyavirus nucleoprotein–RNA complex reveals unique architecture for RNA encapsidation
The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response
Structural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP Binding