Area of research
Pathology and Forensic Medicine · Oncology
Research interest
Research interests include Genetic factors in colorectal cancer, Colorectal Cancer Treatments and Studies, Cancer Genomics and Diagnostics, and Colorectal Cancer Screening and Detection.
Testing for deficient mismatch repair and microsatellite instability
A “Two-in-One Hit” Model of Shortcut Carcinogenesis in MLH1 Lynch Syndrome Carriers
Sex, Genotype, and Liver Volume Progression as Risk of Hospitalization Determinants in Autosomal Dominant Polycystic Liver Disease
Testung auf Mismatch-Reparatur-Defizienz und Mikrosatelliteninstabilität
CpG-biomarkers in tumor tissue and prediction models for the survival of colorectal cancer: A systematic review and external validation study
Erratum zu: Testung auf Mismatch-Reparatur-Defizienz und Mikrosatelliteninstabilität
DNA methylation-based classification of sinonasal tumors
Aktualisierte S2k-Leitlinie Zöliakie der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS)
Mismatch repair deficiency, chemotherapy and survival for resectable gastric cancer: an observational study from the German staR cohort and a meta-analysis
The Different Immune Profiles of Normal Colonic Mucosa in Cancer-Free Lynch Syndrome Carriers and Lynch Syndrome Colorectal Cancer Patients
IDH2 R172 Mutations Across Poorly Differentiated Sinonasal Tract Malignancies
Beta-2-microglobulin Mutations Are Linked to a Distinct Metastatic Pattern and a Favorable Outcome in Microsatellite-Unstable Stage IV Gastrointestinal Cancers
Distinct Mutational Profile of Lynch Syndrome Colorectal Cancers Diagnosed under Regular Colonoscopy Surveillance
A computational model for investigating the evolution of colonic crypts during Lynch syndrome carcinogenesis
Corrigendum to “Conceptual framework for precision cancer medicine in Germany: Consensus statement of the Deutsche Krebshilfe working group ‘Molecular Diagnostics and Therapy’” [European Journal of Cancer 135 (2020) 1-7]
The shared frameshift mutation landscape of microsatellite-unstable cancers suggests immunoediting during tumor evolution
Associations of Pathogenic Variants in MLH1, MSH2, and MSH6 With Risk of Colorectal Adenomas and Tumors and With Somatic Mutations in Patients With Lynch Syndrome
Smoking, alcohol consumption and colorectal cancer risk by molecular pathological subtypes and pathways
The “unnatural” history of colorectal cancer in Lynch syndrome: Lessons from colonoscopy surveillance
<i>TP53</i> Mutations Predict Sensitivity to Adjuvant Gemcitabine in Patients with Pancreatic Ductal Adenocarcinoma: Next-Generation Sequencing Results from the CONKO-001 Trial
The majority of β-catenin mutations in colorectal cancer is homozygous
Conceptual framework for precision cancer medicine in Germany: Consensus statement of the Deutsche Krebshilfe working group ‘Molecular Diagnostics and Therapy’
Age‐dependent performance of <scp> <i>BRAF</i> </scp> mutation testing in Lynch syndrome diagnostics
Malignant transformation and genetic alterations are uncoupled in early colorectal cancer progression
Postmenopausal hormone replacement therapy and colorectal cancer risk by molecular subtypes and pathways
Colonoscopy and Reduction of Colorectal Cancer Risk by Molecular Tumor Subtypes: A Population-Based Case-Control Study
Genetic Variants in the Regulatory T cell–Related Pathway and Colorectal Cancer Prognosis
Colonoscopy and reduction of colorectal cancer risk by molecular tumor subtypes: a population-based case-control study