Area of research
Neurology · Genetics
Research interest
Research interests include Amyotrophic Lateral Sclerosis Research, Neurogenetic and Muscular Disorders Research, Parkinson's Disease Mechanisms and Treatments, and Neurogenesis and neuroplasticity mechanisms.
Primary Lateral Sclerosis Natural History Study: Primary Lateral Sclerosis Functional Rating Scale and Other Outcomes Assessment.
Development of a human iPSC-derived corticospinal tract-on-a-chip
Efficacy and Safety of Zilucoplan in Amyotrophic Lateral Sclerosis
Longitudinal study of gesture decoding in a clinical trial participant with ALS
Development of a Human iPSC-Derived “Corticospinal Tract-on-a-Chip” for Neurodegenerative Disease Research
Self-paced silent speech brain-computer interface for device control
Disease related changes in ATAC-seq of iPSC-derived motor neuron lines from ALS patients and controls
Exploring P2X7 receptor antagonism as a therapeutic target for neuroprotection in an hiPSC motor neuron model.
Altered development and network connectivity in a human neuronal model of 15q11.2 deletion-related neurodevelopmental disorders
Stable Decoding from a Speech BCI Enables Control for an Individual with ALS without Recalibration for 3 Months.
Therapeutic targeting of ALS pathways: Refocusing an incomplete picture.
COURAGE-ALS: a randomized, double-blind phase 3 study designed to improve participant experience and increase the probability of success
COURAGE-ALS: a randomized, double-blind phase 3 study designed to improve participant experience and increase the probability of success.
Phase-Amplitude Coupling Detection and Analysis of Human 2-Dimensional Neural Cultures in Multi-well Microelectrode Array in Vitro
Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines
Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines.
Identifying patterns in amyotrophic lateral sclerosis progression from sparse longitudinal data
Cx43 hemichannels contribute to astrocyte-mediated toxicity in sporadic and familial ALS.
Amyotrophic Lateral Sclerosis Clinical Trials and Interpretation of Functional End Points and Fluid Biomarkers
Publisher Correction: Multi-omic analysis of selectively vulnerable motor neuron subtypes implicates altered lipid metabolism in ALS.
Multi-omic analysis of selectively vulnerable motor neuron subtypes implicates altered lipid metabolism in ALS
Multi-omic analysis of selectively vulnerable motor neuron subtypes implicates altered lipid metabolism in ALS.
MN-166 (ibudilast) in amyotrophic lateral sclerosis in a Phase IIb/III study: COMBAT-ALS study design.
Mini-Review: Induced pluripotent stem cells and the search for new cell-specific ALS therapeutic targets
Phase 1–2 Trial of Antisense Oligonucleotide Tofersen for <i>SOD1</i> ALS
Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis
Addressing heterogeneity in amyotrophic lateral sclerosis CLINICAL TRIALS
Amyotrophic lateral sclerosis care and research in the United States during the <scp>COVID</scp>‐19 pandemic: Challenges and opportunities
Focal and dose-dependent neuroprotection in ALS mice following AAV2-neurturin delivery
Answer ALS: A Large-Scale Resource for Sporadic and Familial ALS Combining Clinical Data with Multi-Omics Data from Induced Pluripotent Cell Lines