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Budd A. Tucker

University of Iowa · US
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Area of research
Molecular Biology · Ophthalmology
Research interest
Research interests include Retinal Development and Disorders, Retinal Diseases and Treatments, CRISPR and Genetic Engineering, and Neuroscience and Neural Engineering.
h-index
57
citations
9,700
works
288
NIH funding
primary concept
email

Recent publications

Using CRISPR-Cas9 to Generate Gene-Corrected Autologous iPSCs for the Treatment of Inherited Retinal Degeneration
Molecular Therapy 2017cited by 142position: lastdoi
Restoration of Aqueous Humor Outflow Following Transplantation of iPSC-Derived Trabecular Meshwork Cells in a Transgenic Mouse Model of Glaucoma
Investigative Ophthalmology & Visual Science 2017cited by 104position: middledoi
Preparation and evaluation of human choroid extracellular matrix scaffolds for the study of cell replacement strategies
Acta Biomaterialia 2017cited by 31position: middledoi
Transplantation of iPSC-derived TM cells rescues glaucoma phenotypes in vivo
Proceedings of the National Academy of Sciences 2016cited by 122position: middledoi
Basal exon skipping and genetic pleiotropy: A predictive model of disease pathogenesis
Science Translational Medicine 2015cited by 84position: middledoi
Generating iPSC-Derived Choroidal Endothelial Cells to Study Age-Related Macular Degeneration
Investigative Ophthalmology & Visual Science 2015cited by 45position: lastdoi
Using patient-specific induced pluripotent stem cells to interrogate the pathogenicity of a novel retinal pigment epithelium-specific 65 kDa cryptic splice site mutation and confirm eligibility for enrollment into a clinical gene augmentation trial
Translational research 2015cited by 29position: firstdoi
Concise Review: Patient-Specific Stem Cells to Interrogate Inherited Eye Disease
Stem Cells Translational Medicine 2015cited by 17position: lastdoi
ABCB5 is a limbal stem cell gene required for corneal development and repair
Nature 2014cited by 277position: middledoi
CEP290 gene transfer rescues Leber congenital amaurosis cellular phenotype
Gene Therapy 2014cited by 127position: lastdoi
Patient-specific induced pluripotent stem cells (iPSCs) for the study and treatment of retinal degenerative diseases
Progress in Retinal and Eye Research 2014cited by 104position: lastdoi
Mechanical properties of murine and porcine ocular tissues in compression
Experimental Eye Research 2014cited by 73position: lastdoi
Stem cells for investigation and treatment of inherited retinal disease
Human Molecular Genetics 2014cited by 64position: firstdoi
Enhanced Differentiation and Delivery of Mouse Retinal Progenitor Cells Using a Micropatterned Biodegradable Thin-Film Polycaprolactone Scaffold
Tissue Engineering Part A 2014cited by 56position: middledoi
Natural History of Cone Disease in the Murine Model of Leber Congenital Amaurosis Due to CEP290 Mutation: Determining the Timing and Expectation of Therapy
PLoS ONE 2014cited by 29position: middledoi
Photoreceptor Cells With Profound Structural Deficits Can Support Useful Vision in Mice
Investigative Ophthalmology & Visual Science 2014cited by 16position: middledoi
Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa
eLife 2013cited by 207position: firstdoi
Non-exomic and synonymous variants in ABCA4 are an important cause of Stargardt disease
Human Molecular Genetics 2013cited by 181position: middledoi
Non-exomic and synonymous variants in ABCA4 are an important cause of Stargardt disease
2013cited by 1position: middle
Use of a Synthetic Xeno-Free Culture Substrate for Induced Pluripotent Stem Cell Induction and Retinal Differentiation
Stem Cells Translational Medicine 2012cited by 96position: firstdoi

Grants

Collaborative Research: RECODE: Microfluidic and genetic technologies to direct and select retinal cell types from human induced pluripotent stem cell-derived retinal organoids
NSF2225488$541,6652022–2026PIRePORTER

Frequent collaborators

Edwin M. Stone · University of Iowa16 papers (2012–2017)Robert F. Mullins · University of Iowa14 papers (2012–2017)Luke A. Wiley · University of Iowa6 papers (2014–2017)Terry A. Braun · University of Iowa4 papers (2013–2014)Erin R. Burnight · University of Iowa4 papers (2014–2017)Arlene V. Drack · University of Iowa3 papers (2013–2014)Val C. Sheffield · University of Iowa3 papers (2013–2017)Artur V. Cideciyan · Penn Presbyterian Medical Center3 papers (2013–2014)Samuel G. Jacobson · California University of Pennsylvania3 papers (2013–2014)Kristin R. Anfinson · University of Iowa3 papers (2012–2017)Allison E. Songstad · University of Iowa3 papers (2014–2015)Megan Riker · University of Iowa3 papers (2013–2017)Alex H. Wagner · The Ohio State University2 papers (2013–2013)Miles J. Flamme‐Wiese · University of Iowa2 papers (2015–2017)Oliver W. Gramlich · Johannes Gutenberg University Mainz2 papers (2016–2017)Wei Zhu · University of Iowa2 papers (2016–2017)Cathryn M. Cranston · University of Iowa2 papers (2015–2015)Michael J. Young · Harvard Stem Cell Institute2 papers (2012–2014)Ankur Jain · University of Iowa2 papers (2016–2017)Kristin Anfinson · University of Iowa2 papers (2013–2015)
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