Area of research
Molecular Biology · Ophthalmology
Research interest
Research interests include Retinal Development and Disorders, Retinal Diseases and Treatments, CRISPR and Genetic Engineering, and Neuroscience and Neural Engineering.
Using CRISPR-Cas9 to Generate Gene-Corrected Autologous iPSCs for the Treatment of Inherited Retinal Degeneration
Restoration of Aqueous Humor Outflow Following Transplantation of iPSC-Derived Trabecular Meshwork Cells in a Transgenic Mouse Model of Glaucoma
Preparation and evaluation of human choroid extracellular matrix scaffolds for the study of cell replacement strategies
Transplantation of iPSC-derived TM cells rescues glaucoma phenotypes in vivo
Basal exon skipping and genetic pleiotropy: A predictive model of disease pathogenesis
Generating iPSC-Derived Choroidal Endothelial Cells to Study Age-Related Macular Degeneration
Using patient-specific induced pluripotent stem cells to interrogate the pathogenicity of a novel retinal pigment epithelium-specific 65 kDa cryptic splice site mutation and confirm eligibility for enrollment into a clinical gene augmentation trial
Concise Review: Patient-Specific Stem Cells to Interrogate Inherited Eye Disease
ABCB5 is a limbal stem cell gene required for corneal development and repair
CEP290 gene transfer rescues Leber congenital amaurosis cellular phenotype
Patient-specific induced pluripotent stem cells (iPSCs) for the study and treatment of retinal degenerative diseases
Mechanical properties of murine and porcine ocular tissues in compression
Stem cells for investigation and treatment of inherited retinal disease
Enhanced Differentiation and Delivery of Mouse Retinal Progenitor Cells Using a Micropatterned Biodegradable Thin-Film Polycaprolactone Scaffold
Natural History of Cone Disease in the Murine Model of Leber Congenital Amaurosis Due to CEP290 Mutation: Determining the Timing and Expectation of Therapy
Photoreceptor Cells With Profound Structural Deficits Can Support Useful Vision in Mice
Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa
Non-exomic and synonymous variants in ABCA4 are an important cause of Stargardt disease
Non-exomic and synonymous variants in ABCA4 are an important cause of Stargardt disease
2013cited by 1position: middle
Use of a Synthetic Xeno-Free Culture Substrate for Induced Pluripotent Stem Cell Induction and Retinal Differentiation