Area of research
Neurology · Plant Science
Research interest
Research interests include Amyotrophic Lateral Sclerosis Research, Chromosomal and Genetic Variations, RNA Research and Splicing, and Neurogenetic and Muscular Disorders Research.
TDP-43 dysregulation of polyadenylation site selection is a defining feature of RNA misprocessing in amyotrophic lateral sclerosis and frontotemporal dementia
TDP-43 loss induces cryptic polyadenylation in ALS/FTD
Author Correction: TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A
LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia
Nuclear RNA catabolism controls endogenous retroviruses, gene expression asymmetry, and dedifferentiation
TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A
Cell environment shapes TDP-43 function with implications in neuronal and muscle disease
An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients
Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia
Diseases of the nERVous system: retrotransposon activity in neurodegenerative disease
Decoding the 5′ nucleotide bias of PIWI-interacting RNAs
Ten things you should know about transposable elements
Unexpected similarities between C9ORF72 and sporadic forms of ALS/FTD suggest a common disease mechanism
NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer
Organoid Models of Human and Mouse Ductal Pancreatic Cancer
An atlas of chromatoid body components
Chd5 Requires PHD-Mediated Histone 3 Binding for Tumor Suppression