Area of research
Organic Chemistry · Oncology
Research interest
Research interests include Click Chemistry and Applications, Peptidase Inhibition and Analysis, Advanced Proteomics Techniques and Applications, and Chemical Synthesis and Analysis.
Delineating cysteine-reactive compound modulation of cellular proteostasis processes
Distributable, metabolic PET reporting of tuberculosis
CysDB: a human cysteine database based on experimental quantitative chemoproteomics
Proximity-labeling chemoproteomics defines the subcellular cysteinome and inflammation-responsive mitochondrial redoxome
SP3-Enabled Rapid and High Coverage Chemoproteomic Identification of Cell-State–Dependent Redox-Sensitive Cysteines
Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation
Photoaffinity labelling strategies for mapping the small molecule–protein interactome
SP3‐FAIMS Chemoproteomics for High‐Coverage Profiling of the Human Cysteinome**
New approaches to target RNA binding proteins
Multiplexed CuAAC Suzuki–Miyaura Labeling for Tandem Activity-Based Chemoproteomic Profiling
Tunable Amine‐Reactive Electrophiles for Selective Profiling of Lysine
Tunable heteroaromatic azoline thioethers (HATs) for cysteine profiling
Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer
Discovery of Reactive Microbiota-Derived Metabolites that Inhibit Host Proteases
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine