Area of research
Molecular Biology · Neurology
Research interest
Research interests include Prion Diseases and Protein Misfolding, Alzheimer's disease research and treatments, Neurological diseases and metabolism, and Trace Elements in Health.
Angiopoietin-like protein 8 directs DNA damage responses towards apoptosis by stabilizing PARP1-DNA condensates.
A rationally designed injury kidney targeting peptide library and its application in rescuing acute kidney injury.
β-synuclein regulates the phase transitions and amyloid conversion of α-synuclein.
A renal YY1-KIM1-DR5 axis regulates the progression of acute kidney injury.
Faculty Opinions recommendation of Donepezil hcl liposomes: development, characterization, cytotoxicity, and pharmacokinetic study.
Faculty Opinions recommendation of A Real-Time Sensing System for Monitoring Neural Network Degeneration in an Alzheimer's Disease-on-a-Chip Model.
Emerging physiological and pathological roles of MeCP2 in non-neurological systems.
Faculty Opinions recommendation of DNA polymerase θ promotes CAG•CTG repeat expansions in Huntington's disease via insertion sequences of its catalytic domain.
Faculty Opinions recommendation of TNF-α-mediated reduction in inhibitory neurotransmission precedes sporadic Alzheimer's disease pathology in young Trem2R47H rats.
Faculty Opinions recommendation of When Cognitive Decline and Depression Coexist in the Elderly: CSF Biomarkers Analysis Can Differentiate Alzheimer's Disease from Late-Life Depression.
Faculty Opinions recommendation of Continuous Monitoring of Tau-Induced Neurotoxicity in Patient-Derived iPSC-Neurons.
Faculty Opinions recommendation of An astrocyte cell line that differentially propagates murine prions.
Faculty Opinions recommendation of TDP-43 inhibitory peptide alleviates neurodegeneration and memory loss in an APP transgenic mouse model for Alzheimer's disease.
Faculty Opinions recommendation of α-Synuclein filaments from transgenic mouse and human synucleinopathy-containing brains are major seed-competent species.
Faculty Opinions recommendation of Long noncoding RNA 00507/miRNA-181c-5p/TTBK1/MAPT axis regulates tau hyperphosphorylation in Alzheimer's disease.
Faculty Opinions recommendation of Young blood plasma reduces Alzheimer's disease-like brain pathologies and ameliorates cognitive impairment in 3×Tg-AD mice.
Faculty Opinions recommendation of Parkinson's disease and multiple system atrophy have distinct α-synuclein seed characteristics.
Faculty Opinions recommendation of Trisomy of human chromosome 21 enhances amyloid-β deposition independently of an extra copy of APP.
Faculty Opinions recommendation of Does SCFD1 rs10139154 Polymorphism Decrease Alzheimer's Disease Risk?
Faculty Opinions recommendation of A farnesyltransferase inhibitor activates lysosomes and reduces tau pathology in mice with tauopathy.
Prion seeding activity and infectivity in skin samples from patients with sporadic Creutzfeldt-Jakob disease
Selective Translation and Degradation of Heat-ShockMessenger RNAs in Drosophila
Quiescin-sulfhydryl oxidase inhibits prion formation in vitro
Prion Protein Protects against Renal Ischemia/Reperfusion Injury
Parallels Between Major Depressive Disorder and Alzheimer’s Disease: Role of Oxidative Stress and Genetic Vulnerability
Glycoform-Selective Prion Formation in Sporadic and Familial Forms of Prion Disease
Recombinant Human Prion Protein Inhibits Prion Propagation in vitro
Correction: Glycoform-Selective Prion Formation in Sporadic and Familial Forms of Prion Disease
Activation of the extracellular signal‐regulated kinase pathway contributes to the behavioral deficit of fragile x‐syndrome
PrPSc detection and infectivity in semen from scrapie-infected sheep