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Francesca Tuorto

University of Mannheim · DE
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Area of research
Molecular Biology
Research interest
Research interests include RNA modifications and cancer, RNA and protein synthesis mechanisms, Epigenetics and DNA Methylation, and Developmental Biology and Gene Regulation.
h-index
32
citations
6,039
works
65
NIH funding
primary concept
email

Recent publications

The two-step purification method ViREn identifies a single NSUN6-mediated 5-methylcytosine modification promoting dengue virus RNA genome turnover
Nucleic Acids Research 2026cited by 1position: middledoi
TGT Damages its Substrate tRNAs by the Formation of Abasic Sites in the Anticodon Loop
Journal of Molecular Biology 2025cited by 4position: middledoi
Queuosine is incorporated into precursor tRNA before splicing
Nature Communications 2025cited by 3position: lastdoi
<scp>Queuosine‐tRNA</scp> promotes sex‐dependent learning and memory formation by maintaining codon‐biased translation elongation speed
The EMBO Journal 2023cited by 44position: lastdoi
Functional integration of a semi-synthetic azido-queuosine derivative into translation and a tRNA modification circuit
Nucleic Acids Research 2022cited by 13position: middledoi
Correction to ‘RiboVIEW: a computational framework for visualization, quality control and statistical analysis of ribosome profiling data’
Nucleic Acids Research 2022cited by 0position: lastdoi
RNA marker modifications reveal the necessity for rigorous preparation protocols to avoid artifacts in epitranscriptomic analysis
Nucleic Acids Research 2021cited by 30position: middledoi
Analysis of Queuosine tRNA Modification Using APB Northern Blot Assay
Methods in molecular biology 2021cited by 15position: lastdoi
Translational adaptation to heat stress is mediated by RNA 5‐methylcytosine in <i>Caenorhabditis elegans</i>
The EMBO Journal 2020cited by 43position: middledoi
Queuine Micronutrient Deficiency Promotes Warburg Metabolism and Reversal of the Mitochondrial ATP Synthase in Hela Cells
Nutrients 2020cited by 38position: middledoi
Sperm RNA code programmes the metabolic health of offspring
Nature Reviews Endocrinology 2019cited by 278position: middledoi
Queuine links translational control in eukaryotes to a micronutrient from bacteria
Nucleic Acids Research 2019cited by 98position: middledoi
rRNA and tRNA Bridges to Neuronal Homeostasis in Health and Disease
Journal of Molecular Biology 2019cited by 32position: firstdoi
Division of labour: tRNA methylation by the NSun2 tRNA methyltransferases Trm4a and Trm4b in fission yeast
RNA Biology 2019cited by 21position: middledoi
RiboVIEW: a computational framework for visualization, quality control and statistical analysis of ribosome profiling data
Nucleic Acids Research 2019cited by 20position: lastdoi
Dnmt2 mediates intergenerational transmission of paternally acquired metabolic disorders through sperm small non-coding RNAs
Nature Cell Biology 2018cited by 488position: middledoi
Queuosine‐modified tRNAs confer nutritional control of protein translation
The EMBO Journal 2018cited by 203position: firstdoi
Loss of Proteostasis Is a Pathomechanism in Cockayne Syndrome
Cell Reports 2018cited by 57position: middledoi
BisAMP: A web-based pipeline for targeted RNA cytosine-5 methylation analysis
Methods 2018cited by 20position: middledoi
806 A circulus vitiosus causes loss of proteostasis in Cockayne syndrome
Journal of Investigative Dermatology 2018cited by 0position: middledoi
Statistically robust methylation calling for whole-transcriptome bisulfite sequencing reveals distinct methylation patterns for mouse RNAs
Genome Research 2017cited by 215position: middledoi
Ribosomal transcription is regulated by PGC-1alpha and disturbed in Huntington’s disease
Scientific Reports 2017cited by 40position: middledoi
Statistically robust methylation calling for whole-transcriptome bisulfite sequencing reveals distinct methylation patterns for mouse RNAs
bioRxiv (Cold Spring Harbor Laboratory) 2017cited by 17position: middledoi
Declined presentation loss of tRNA-methylation at cytosine 38 by Dnmt2 induces a hematopoietic stem cell aging-like phenotype
Experimental Hematology 2017cited by 1position: middledoi
Genome recoding by tRNA modifications
Open Biology 2016cited by 97position: firstdoi
The <scp>tRNA</scp> methyltransferase Dnmt2 is required for accurate polypeptide synthesis during haematopoiesis
The EMBO Journal 2015cited by 232position: firstdoi
RNA–Mediated Epigenetic Heredity Requires the Cytosine Methyltransferase Dnmt2
PLoS Genetics 2013cited by 204position: middledoi
The Mouse Cytosine-5 RNA Methyltransferase NSun2 Is a Component of the Chromatoid Body and Required for Testis Differentiation
Molecular and Cellular Biology 2013cited by 148position: middledoi
RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis
Nature Structural & Molecular Biology 2012cited by 653position: firstdoi
Extensive Methylation of Promoter Sequences Silences Lentiviral Transgene Expression During Stem Cell Differentiation In Vivo
Molecular Therapy 2012cited by 108position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Frank Lyko · German Cancer Research Center16 papers (2012–2023)Carine Legrand · Centre National de la Recherche Scientifique10 papers (2017–2023)Mark Helm · Johannes Gutenberg University Mainz9 papers (2012–2025)Cansu Cirzi · German Cancer Research Center7 papers (2018–2025)Reinhard Liebers · Vienna Vaccine Safety Initiative6 papers (2012–2018)Ann E. Ehrenhofer‐Murray · Humboldt-Universität zu Berlin4 papers (2018–2022)Georg Stoecklin · University of Mannheim4 papers (2012–2026)Rosanna Parlato · University of Mannheim4 papers (2018–2023)Karin Scharffetter‐­Kochanek · Universität Ulm3 papers (2017–2018) · 3 papers (2017–2018)Hanno Glimm · Metropolitan University3 papers (2012–2017) · 3 papers (2017–2018)Wei Guo · DKFZ-ZMBH Alliance3 papers (2023–2025)Kevin Kopietz · Johannes Gutenberg University Mainz3 papers (2025–2026)Gunnar Dittmar · Charité - Universitätsmedizin Berlin3 papers (2015–2023)Martin Müller · German Cancer Research Center3 papers (2018–2019) · 2 papers (2019–2020)Friederike Herbst · Parker Institute for Cancer Immunotherapy2 papers (2015–2017) · 2 papers (2018–2018) · 2 papers (2013–2019)
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